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. 2008 Oct 7;99(9):1395–1401. doi: 10.1038/sj.bjc.6604708

Table 3. Number of patients with dose-limiting toxicity (DLT) by dose level.

Dose level 1 (n=6) 2 (n=6) 3 (n=6) 4 (n=7) 5 (n=5) Combined (n=30)
Number of patients with DLT 2 1 2 1 3 9
Number of DLTs 3 2 3 1 3 12
             
Type of DLT
 Anorexia 1 1 1 1 4
 Asthenia 1 1 2 4
 Epithelitis 1 1
 Febrile neutropenia 1 1
 Infection 1 1
 Diarrhoea 1 1