Table 2. HLA class I expression of tumours in relation to clinicopathologic status.
|
HLA class I expression in primary lesion
|
||||
|---|---|---|---|---|
| Strong (n=40) | Weak (n=24) | Absent (n=6) | ||
| Stage a | ||||
| I (n=14) | 12 | 1 | 1 | |
| IIA (n=16) | 7 | 8 | 1 | ** |
| IIB (n=16) | 11 | 2 | 3 | |
| III (n=24) | 10 | 13 | 1 | |
| Tumour a | ||||
| T1 (n=28) | 22 | 3 | 3 | |
| T2 (n=5) | 1 | 3 | 1 | ** |
| T3 (n=34) | 15 | 17 | 2 | |
| T4 (n=3) | 2 | 1 | 0 | |
| Lymph node metastasis a | ||||
| N0 (n=30) | 19 | 9 | 2 | |
| N1 (n=40) | 21 | 15 | 4 | NS |
| Histological classification | ||||
| Well (n=15) | 7 | 8 | 0 | |
| Moderately (n=38) | 27 | 10 | 1 | ** |
| Poorly (n=17) | 6 | 6 | 5 | |
Abbreviations: Moderately=moderately differentiated squamous cell carcinoma; NS=not significant; poorly=poorly differentiated squamous cell carcinoma; Well=well-differentiated squamous cell carcinoma.
**P<0.05 by the χ2 test.
a
Tumour, lymph node metastasis, and stage according to the TNM classification for esophageal cancer (UICC).