Table 4. BMI and risk of oesophageal and cardia adenocarcinoma expressed in OR with 95% CI.
|
Women
|
Men
|
|||||
|---|---|---|---|---|---|---|
| Controls | Cases | ORa | Controls | Cases | ORa | |
| Variables | N=140 (%) | N=63 (%) | (95% CI) | N=676 (%) | N=388 (%) | (95% CI) |
| BMI maximum as adult | ||||||
| <22 | 18 (13) | 2 (3) | 1.0 (reference) | 40 (6) | 12 (3) | 1.0 (reference) |
| 22–24.9 | 44 (31) | 11 (17) | 1.1 (0.2–6.3) | 198 (29) | 77 (20) | 1.1 (0.5–2.4) |
| 25–29.9 | 56 (40) | 26 (41) | 3.1 (0.6–16.9) | 335 (50) | 208 (54) | 1.8 (0.9–3.6) |
| ⩾30 | 22 (16) | 24 (38) | 6.5 (1.1–39.0) | 103 (15) | 91 (23) | 2.2 (1.1–4.7) |
| BMI minimum as adult | ||||||
| <22 | 112 (80) | 32 (51) | 1.0 (reference) | 352 (52) | 147 (38) | 1.0 (reference) |
| 22–24.9 | 23 (16) | 24 (38) | 4.1 (1.7–9.6) | 270 (40) | 183 (47) | 1.6 (1.2–2.2) |
| ⩾25 | 5 (4) | 7 (12) | 7.6 (1.9–30.5) | 54 (8) | 58 (15) | 2.7(1.7–4.2) |
| BMI change during adult life | ||||||
| >2 | 15 (11) | 4 (6) | 1.0 (reference) | 121 (18) | 59 (15) | 1.0 (reference) |
| 2–4.9 | 51 (36) | 22 (35) | 1.3 (0.3–5.5) | 283 (42) | 155 (40) | 1.0 (0.6–1.4) |
| 5–8.9 | 53 (38) | 21 (33) | 1.0 (0.2–4.0) | 214 (32) | 128 (33) | 1.0 (0.7–1.5) |
| ⩾9 | 21 (15) | 16 (25) | 2.0 (0.4–8.8) | 58 (9) | 45 (12) | 1.1 (0.6–1.9) |
BMI=body mass index; CI=confidence interval; OR=odds ratio.
a
Adjustments were made for age, educational level, alcohol use, gastro-oesophageal reflux, cigarette smoking, intake of fruits and vegetables, and Helicobacter pylori infection.