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. Author manuscript; available in PMC: 2008 Nov 5.
Published in final edited form as: Parasitol Res. 2005 Jun 29;97(2):136–140. doi: 10.1007/s00436-005-1406-7

Table 1.

Prevalence of pfcrt and pfmdr1 polymorphisms in relation to in vitro CQ susceptibility

Polymorphism CQ susceptible# isolates (proportion) CQ resistant# isolates (proportion) P value
Pfcrt K76 11/17 (0.65) 2/19 (0.11) < 0.05
Pfcrt T76 6/17 (0.35) 17/19 (0.89)
Pfmdr1 N86 13/17 (0.76) 12/19 (0.63) 0.6
Pfmdr1 Y86 4/17 (0.24) 7/19 (0.37)

Note: In vitro CQ susceptibility is defined as IC50 values less or equal to 100 nM

a

Average 51, range 11–102 nM, CI 37–64

b

Average 474; range 120–2,153 nM, CI 273–577