Table 1.
Polymorphism | CQ susceptible# isolates (proportion) | CQ resistant# isolates (proportion) | P value |
---|---|---|---|
Pfcrt K76 | 11/17 (0.65) | 2/19 (0.11) | < 0.05 |
Pfcrt T76 | 6/17 (0.35) | 17/19 (0.89) | |
Pfmdr1 N86 | 13/17 (0.76) | 12/19 (0.63) | 0.6 |
Pfmdr1 Y86 | 4/17 (0.24) | 7/19 (0.37) |
Note: In vitro CQ susceptibility is defined as IC50 values less or equal to 100 nM
Average 51, range 11–102 nM, CI 37–64
Average 474; range 120–2,153 nM, CI 273–577