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Risk of colorectal liver metastases associated with the p53 R72P polymorphism stratified by p53 overexpression
| p53 overexpression | p53 R72P | Nonmetastases, n | Metastases, n | ORa | Pa |
| Positive | PP | 20 (27.0%) | 4 (9.3%) | 1.00 | |
| R carriers | 54 (73.0%) | 39 (90.7%) | 3.46 (95% CI=1.02~11.72) | 0.046 | |
| Negative | PP | 18 (20.2%) | 7 (21.2%) | 1.00 | |
| R carriers | 71 (79.8%) | 26 (78.8%) | 1.05 (95% CI=0.36~3.08) | 0.935 |
Adjusted for the depth of invasion and lymph node metastasis
