Fig. 8.4.

3D structure of bovine heart supercomplex I ₁III₂IV₁. The globular 3D structure of the supercomplex is overlayed with the crystal structures of the Complex III dimer and Complex IV monomer as indicated. The face of Complex III that interacts with Complex IV is shown in Fig. 8.3B. The close proximity of the cytochrome c binding sites on Complexes III and IV is indicated. The organization of the supercomplex and cytochrome c interaction shown in Fig. 8.5 is based on this structure. Figure adapted from (Schafer et al., 2007)