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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Nat Struct Mol Biol. 2008 Oct 19;15(11):1152–1159. doi: 10.1038/nsmb.1507

Figure 5.

Figure 5

Asn172 may contribute to Mg2+ coordination. (a) Mean G-V relationship of WT, N172D and N172K mutant channels in 0 and 10 mM [Mg2+]i. (b) Shifts of the G-V relationship caused by 10 mM [Mg2+]i for WT and Gln397, Tyr336, and Asn172 mutations. (c) Shifts of the G-V relationship caused by 10 mM [Mg2+]i. Inset, N172D may substitute other putative Mg2+ coordinates to enable Mg2+ binding.