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. 2008 Oct 29;2:4. doi: 10.3389/neuro.04.004.2008

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Copyright © 2008 Rinaldi, Perrodin and Markram.

This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.

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Enhanced long-term potentiation in layer 5 pyramidal neurons. (A) Experimental scheme and pairing protocol; example of mean response in a patched cell, before and after pairing. (B) Example of response amplitude as a function of time (the grey line represents the timing of the pairing protocol); mean absolute values for control (blue) and treated (red) rats before pairing (t = 0) and at three different times after pairing. (C) Mean of percentage increase in the amplitude of the response to extracellular stimulation 30 min after pairing. Data show mean ± SEM (**P < 0.01).