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. 1991 Jul;59(7):2502–2504. doi: 10.1128/iai.59.7.2502-2504.1991

Somnogenic activity of pseudomurein in rabbits.

L Johannsen 1, H Labischinski 1, J M Krueger 1
PMCID: PMC258039  PMID: 2050415

Abstract

Pseudomurein is a major cell wall component of some archaebacteria that chemically differs from but morphologically, functionally, and structurally resembles eubacterial peptidoglycan. Eubacterial cell wall components, e.g., peptidoglycan, induce changes in sleep and body temperature. We now report that intravenous injections of rabbits with a suspension of pseudomurein from Methanobacterium thermoautotrophicum also induce similar central nervous system effects.

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Selected References

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