Table 2. Degree centrality of the conditional networks.

Conditional Networks	Number of High Degree Nodes	Networks Compared	Common Nodes	Criticality	Number of Proteins
UWT	570	UWT-TWT	527	Mutation independent	104
TWT	560	UML-TML	523	Mutation dependent	100
UML	587	UWT-UML	465	UV independent	42
TML	584	TWT-TML	480	UV dependent	57

The analysis of the top 30% nodes in terms of degree centrality alone in each conditional network revealed the nodes that are proposed to be essential depending on the UV treatment or the mutation. UWT, UV Untreated Wild Type; TWT, UV Treated Wild Type; UML, UV Untreated lexA mutant; TML, UV Treated lexA mutant.