Table 2.
SBR50 vs. Sham | SBR50/IL-6 vs. SBR50 | SBR50/IL/6/Gvs.SBR50/IL-6 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
mRNA Probeset Number | Gene Name* | Gene Symbol | Fold P/Sham | FDR† | Fold IL-6/p | FDR† | Fold G/IL-6 | FDR† | ||||||
GROUP IA | GENES INCREASED IN SBR50 vs. SHAM AND DECREASED IN SBR50/IL-6 vs. SBR50 | |||||||||||||
NM_012620 | serine (or cysteine) peptidase inbitior, clade E, member 1 | Serpine1 | 29.09 | 0.000 | 0.25 | 0.004 | 1.73 | 0.147 | ||||||
B1284218 | solute carrier family 2 (faciliated glucose transporter), member 1 | Slc2a1 | 20.29 | 0.000 | 0.26 | 0.002 | 1.72 | 0.079 | ||||||
NM_012580 | heme oxygenase (decycling) 1 | Hmoxl | 19.97 | 0.002 | 0.13 | 0.020 | 1.20 | 0.846 | ||||||
M58040 | transferrin receptor | Tfrc | 10.82 | 0.000 | 0.39 | 0.044 | 1.07 | 0.899 | ||||||
D64048 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 | Pik3rl | 6.17 | 0.003 | 0.21 | 0.014 | 0.64 | 0.433 | ||||||
U02315 | neuregulin 1 | Nrg1 | 5.08 | 0.002 | 0.43 | 0.062 | 0.70 | 0.428 | ||||||
NM_017334 | cAMP responsive element modulator | 3081 | 0.001 | 0.59 | 0.079 | 0.57 | 0.078 | |||||||
AI172056 | myeloid cell leukemia sequence 1 | Mcl1 | 3.43 | 0.001 | 0.46 | 0.019 | 0.87 | 0.669 | ||||||
NM_080902 | hypoxia induced gene 1 | Hig1 | 3032 | 0.001 | 0.36 | 0.005 | 1.09 | 0.773 | ||||||
AF279286 | Bc12-like 1 | Bc1211 | 3023 | 0.001 | 0.40 | 0.007 | 1.36 | 0.300 | ||||||
BI290699 | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | Pik3ca | 3.18 | 0.000 | 0.31 | 0.002 | 0.90 | 0.692 | ||||||
NM_019142 | protein kinase, AMP-activated, alpha 1 catalytic subunit | Prkaa1 | 3.08 | 0.000 | 0.42 | 0.004 | 1.12 | 0.657 | ||||||
L062638 | platelet derived growth factor, alpha | Pdgfa | 3.00 | 0.002 | 0.43 | 0.015 | 1.05 | 0.885 | ||||||
U69550 | phospholipase D1 | PlaD1 | 2.72 | 0.000 | 0.54 | 0.009 | 0.98 | 0.945 | ||||||
AB001382 | secreted phosphoprotein 1 | Sppl | 2.67 | 0.013 | 0.45 | 0.048 | 2.08 | 0.077 | ||||||
NM_013052 | tyrosine 3-monooxygenase/tyrptophan 5-monooxygenase activation protein, eta polypeptide | Ywhah | 2.42 | 0.002 | 0.66 | 0.095 | 2.95 | 0.001 | ||||||
NM_053843 | Fc receptor, IgG, low affinity III /// Fc gamma receptor II beta | Fcgr3 | 2.37 | 0.002 | 0.52 | 0.019 | 1.67 | 0.058 | ||||||
NM_017039 | protein phosphate 2 (formerly 2A), catalytic subunit, alpha isoform | Ppp2ca | 2.33 | 0.001 | 0.59 | 0.018 | 1.76 | 0.015 | ||||||
BE113920 | signal transducer and activator of transcription 3 | Stat3 | 2.33 | 0.086 | 0.38 | 0.068 | 1.57 | 0.395 | ||||||
NM_019376 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | Ywhag | 2.30 | 0.000 | 0.57 | 0.004 | 1.35 | 0.059 | ||||||
NM_053887 | mitogen activated protein kinase kinase kinase 1 | Map3k1 | 2.24 | 0.036 | 0.38 | 0.022 | 1.19 | 0.686 | ||||||
NM_031140 | Vimentin | Vim | 2.19 | 0.001 | 0.51 | 0.004 | 1.66 | 0.018 | ||||||
NM_031514 | Janus kinase 2 | Jak2 | 2.18 | 0.017 | 0.049 | 0.037 | 0.96 | 0.917 | ||||||
NM_031832 | lectin, galactose binding, soluble 3 | Lgals3 | 2.03 | 0.066 | 0.46 | 0.061 | 2.58 | 0.033 | ||||||
NM_019232 | serum/glucocorticoid regulated kinase | Sgk | 2.00 | 0.080 | 0.47 | 0.074 | 0.94 | 0.902 | ||||||
AI409867 | cystatin B | CstB | 1.89 | 0.002 | 0.55 | 0.007 | 1.41 | 0.080 | ||||||
NM_017255 | purinergic receptor P2Y, G-protein coupled 2 | P2ryl | 1.82 | 0.006 | 0.49 | 0.005 | 1.46 | 0.082 | ||||||
NM_017022 | integrin beta 1 (fibronectin receptor beta) | Itgbl | 1.82 | 0.001 | 0.61 | 0.006 | 1.15 | 0.351 | ||||||
NM_012886 | tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) | Timp3 | 1.80 | 0.022 | 0.64 | 0.093 | 0.95 | 0.859 | ||||||
AI600237 | eukaryotic translation elongation factor 1 epsilon 1 (predicted) | Eefle1 | 1.79 | 0.008 | 0.67 | 0.061 | 0.72 | 0.135 | ||||||
AF228684 | adenosine A2a receptor | Adora2a | 1.76 | 0.006 | 0.60 | 0.016 | 1.93 | 0.005 | ||||||
BE108192 | G1 to S phase transition 1 | Gspt1 | 1.74 | 0.000 | 0.70 | 0.004 | 1.03 | 0.772 | ||||||
NM_053619 | complement component 5, receptor 1 | C5rl | 1.73 | 0.003 | 0.51 | 0.004 | 1.84 | 0.004 | ||||||
B1285434 | tubulin, alpha 1 /// tubulin, alpha 6 /// similar to Tubulin alpha-2 chain (Alpha-tubulin 2) (predicted) | Tubal | 1.73 | 0.002 | 0.62 | 0.010 | 1.65 | 0.008 | ||||||
BM385544 | presenilin 1 | Psen1 | 1.67 | 0.008 | 0.65 | 0.029 | 1.80 | 0.008 | ||||||
BF281342 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | Ywhaq | 1.63 | 0.001 | 0.69 | 0.009 | 1.09 | 0.463 | ||||||
NM_021989 | tissue inhibitor of metalloproteinase 2 | Timp2 | 1.56 | 0.002 | 0.68 | 0.009 | 0.82 | 0.135 | ||||||
AI236590 | myeloid differentiation primary response gene 88 | Myd88 | 1.56 | 0.044 | 0.56 | 0.019 | 1.30 | 0.272 | ||||||
BM392321 | Homeodomain interacting protein kinase 2 (predicted) | Hipk2_predicted | 1.53 | 0.026 | 0.69 | 0.068 | 0.88 | 0.534 | ||||||
BG379941 | Harvey rat sarcoma viral (v-Ha-Ias) oncogene homolog | HraS | 1.52 | 0.003 | 0.73 | 0.025 | 1.28 | 0.079 | ||||||
BF417479 | 24-dehydrocholestrol reductase | Dhcr24 | 1.51 | 0.015 | 0.69 | 0.038 | 0.63 | 0.018 | ||||||
NM_017141 | polymerase (DNA directed), beta | Polb | 1.51 | 0.075 | 0.61 | 0.048 | 1.46 | 0.134 | ||||||
NM_031787 | Homeodomain interacting protein kinase 3 | Hipk3 | 1.50 | 0.093 | 0.52 | 0.019 | 0.59 | 0.060 | ||||||
AA893484 | fibronectin 1 | Fank1 | 1.49 | 0.028 | 0.64 | 0.022 | 0.74 | 0.116 | ||||||
AI172276 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | Ppplr2 | 1.47 | 0.008 | 0.79 | 0.092 | 1.06 | 0.727 | ||||||
NM_053720 | apoptosis antagonizing transcription factor | Aatf | 1.46 | 0.070 | 0.58 | 0.021 | 1.17 | 0.490 | ||||||
M37394 | epidermal growth factor receptor | Hgfr | 1.44 | 0.092 | 0.52 | 0.012 | 0.52 | 0.014 | ||||||
BG666933 | cystatin C | CstC | 1.40 | 0.002 | 0.77 | 0.014 | 0.71 | 0.004 | ||||||
BM389673 | cofilin 1, non-muscle | Cfl1 | 1.39 | 0.086 | 0.61 | 0.021 | 1.33 | 0.171 | ||||||
EE111972 | transforming growth factor, beta receptor 1 | Trfbr1 | 1.37 | 0.090 | 0.63 | 0.027 | 0.92 | 0.680 | ||||||
AF388527 | Serpinel mRNA binding protein 1 | Serbp1 | 1.31 | 0.016 | 0.83 | 0.096 | 1.11 | 0.365 | ||||||
NM_0131315 | RAS p21 protein activator 1 | Rasal | 1.28 | 0.033 | 0.66 | 0.005 | 1.04 | 0.771 | ||||||
B1282863 | Prohibition | Phb | 1.26 | 0.092 | 0.76 | 0.069 | 0.70 | 0.026 | ||||||
BI282281 | heat shock 70kDa protein 9A (predicted) | Hspa9a_predicted | 1.22 | 0.012 | 0.73 | 0.004 | 0.75 | 0.004 | ||||||
AI103616 | ras-related C3 botulimum toxin substrate 1 | Rax1 | 1.21 | 0.029 | 0.74 | 0.007 | 1.31 | 0.012 | ||||||
NM_019371 | EGL nine homolog 3 | Egin3 | 17.30 | 0.000 | 0.07 | 0.000 | 0.81 | 0.493 | ||||||
AI602811 | dual specificity phosphatase 6 | Dusp6 | 15.48 | 0.000 | 0.44 | 0.012 | 1.27 | 0.418 | ||||||
BI303379 | tumor necrosis factor receptor superfamily, member 12a | Tnfrsf12a | 9.82 | 0.002 | 0.29 | 0.064 | 2.08 | 0.277 | ||||||
NM_012591 | interferon regulatory factor 1 | Irf1 | 9.32 | 0.000 | 0.39 | 0.005 | 1.33 | 0.311 | ||||||
NM_133306 | oxidized low density lipoprotein (lectin-like) receptor 1 | Oldlr1 | 9.02 | 0.000 | 0.30 | 0.004 | 2.01 | 0.041 | ||||||
NM_024127 | growth arrest and DNA-damage-inducible 45 alpha | Gadd45a | 6.25 | 0.001 | 0.50 | 0.098 | 1.95 | 0.130 | ||||||
NM_053420 | BCL2/adenovirus E1B 19 kDa-interacting protein 3 | Bnip3 | 6.07 | 0.000 | 0.19 | 0.002 | 0.88 | 0.734 | ||||||
AI232697 | phosphatidylserine receptor | Jmjd6 | 3.51 | 0.007 | 0.43 | 0.058 | 0.89 | 0.802 | ||||||
NM_021846 | similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase like 1)(predicted) | RGD1561096 | 3.46 | 0.001 | 0.43 | 0.018 | 0.86 | 0.662 | ||||||
B1287978 | growth arrest and DNA-damage-inducible 45 beta | Gadd45b | 3.20 | 0.002 | 0.54 | 0.061 | 1.33 | 0.383 | ||||||
NM_021744 | CD14 antigen | Cd14 | 3.07 | 0.003 | 0.49 | 0.039 | 0.73 | 0.362 | ||||||
NM_012637 | protein tyrosine phosphatase, non-receptor type 1 | Ptpn1 | 3.02 | 0.007 | 0.35 | 0.015 | 0.47 | 0.069 | ||||||
B1275994 | transglutaminase 2, C polypeptide | Tgm2 | 2.98 | 0.000 | 0.45 | 0.004 | 2.99 | 0.000 | ||||||
NM_013026 | syndecan 1 | Sdc1 | 2.91 | 0.000 | 0.48 | 0.005 | 2.92 | 0.001 | ||||||
B1284739 | LPS-induced TN factor | Litaf | 2.70 | 0.000 | 0.50 | 0.005 | 1.23 | 0.289 | ||||||
J04943 | nucleophosmin 1 /// similar to Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin)(Nucleolar protein NO348) | Npm1 /// LOC300303 | 2.67 | 0.001 | 0.50 | 0.010 | 1.42 | 0.152 | ||||||
AB049572 | sphingosine kinase 1 | Sphk1 | 2.63 | 0.002 | 0.61 | 0.067 | 0.60 | 0.074 | ||||||
AI411788 | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | Ppp2f1b | 2.63 | 0.000 | 0.39 | 0.002 | 1.55 | 0.049 | ||||||
B1289109 | max binding protein (predicted) | Mnt | 2.44 | 0.004 | 0.51 | 0.027 | 1.40 | 0.258 | ||||||
X57764 | endothelin receptor type B | Ednrb | 2.43 | 0.002 | 0.58 | 0.028 | 1.11 | 0.673 | ||||||
NM_134432 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Agt | 2.11 | 0.002 | 0.43 | 0.004 | 1.31 | 0.233 | ||||||
AF136231 | caspase 2 | Casp2 | 2.04 | 0.009 | 0.38 | 0.004 | 0.86 | 0.592 | ||||||
BM387008 | caspase 3, apoptosis related cysteine protease | Casp3 | 2.00 | 0.001 | 0.54 | 0.004 | 1.46 | 0.037 | ||||||
DI3341 | mitogen activated protein kinase kinase 1 | Map2k1 | 1.96 | 0.007 | 0.62 | 0.055 | 1.81 | 0.026 | ||||||
NM_053974 | eukaryotic translation initation factor 4E | Eif4eb 1 | 1.92 | 0.003 | 0.64 | 0.028 | 1.12 | 0.584 | ||||||
AF066016 | nuclear receptor subfamily 3, group C, member 1 | Nr-3c1 | 1.85 | 0.006 | 0.59 | 0.022 | 1.10 | 0.680 | ||||||
BF283772 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Rela | 1.67 | 0.012 | 0.71 | 0.091 | 1.27 | 0.256 | ||||||
NM_013091 | tumor necrosis factor receptor superfamily, member 1a | Trfrsf1a | 1.62 | 0.036 | 0.54 | 0.017 | 2.08 | 0.009 | ||||||
NM_017040 | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform | Ppp2cb | 1.60 | 0.002 | 0.64 | 0.005 | 0.98 | 0.899 | ||||||
BM386683 | Stanniocalcin 1 | Stc1 | 1.59 | 0.016 | 0.65 | 0.033 | 0.80 | 0.264 | ||||||
AI012221 | chloride intracellular channel 1 | Clic1 | 1.59 | 0.002 | 0.77 | 0.149 | 1.82 | 0.001 | ||||||
B1282898 | BCL2-associated athanogene 5 | Bag5 | 1.57 | 0.002 | 0.61 | 0.004 | 0.78 | 0.077 | ||||||
B1296393 | programmed cell death 6 (predicted) | Pdcd6 | 1.49 | 0.002 | 0.70 | 0.007 | 1.23 | 0.083 | ||||||
AI169001 | antophagy-related 12 (yeast) | Atg12 | 1.47 | 0.004 | 0.65 | 0.006 | 0.90 | 0.387 | ||||||
B1285751 | cullin 3 (predicted) | Cu13_predicted | 1.46 | 0.012 | 0.62 | 0.006 | 0.87 | 0.373 | ||||||
NM_133307 | protein kinase C, delta | Prkcd | 1.42 | 0.025 | 0.73 | 0.058 | 1.23 | 0.207 | ||||||
B1289418 | CD38 antigen | Cd38 | 1.42 | 0.091 | 0.68 | 0.088 | 1.19 | 0.433 | ||||||
NM_012696 | kininogen 1 /// K-kininogen /// similar to alpha-1 major acute phase protein prepeptide | Kng1 | 1.42 | 0.019 | 0.68 | 0.019 | 1.84 | 0.002 | ||||||
AA859665 | Nuclear pore associated protein | Npap60 | 1.40 | 0.012 | 0.69 | 0.012 | 0.89 | 0.401 | ||||||
NM_080887 | thioredoxin-like 1 | Txnll | 1.39 | 0.002 | 0.74 | 0.007 | 1.24 | 0.034 | ||||||
AA848545 | similar to programmed cell death 10 | Pdcd10 | 1.38 | 0.063 | 0.61 | 0.016 | 1.52 | 0.033 | ||||||
NM_012839 | cytochrome c, somatic | Cycs | 1.38 | 0.001 | 0.77 | 0.007 | 1.03 | 0.772 | ||||||
B1282255 | ribosomal protein S5 | Rps5 | 1.34 | 0.001 | 0.85 | 0.025 | 0.78 | 0.005 | ||||||
NM_022510 | ribosomal protein L4 | Rp14 | 1.33 | 0.031 | 0.73 | 0.025 | 0.75 | 0.044 | ||||||
AF411318 | metallothionein 1a | MtIa | 1.29 | 0.058 | 0.62 | 0.006 | 0.90 | 0.456 | ||||||
NM_013065 | protein phosphatase 1, catalytic subunit, beta isoform | Ppp2cb | 1.26 | 0.051 | 0.75 | 0.028 | 0.98 | 0.865 | ||||||
B1283681 | eukaryotic translation initation factor 5A | Eif5a | 1.25 | 0.031 | 0.77 | 0.023 | 1.29 | 0.031 | ||||||
NM_080888 | BCL2/adenovirus E1B 19 kDa-interacting protein 3-like | Bnip31 | 1.19 | 0.077 | 0.73 | 0.010 | 0.60 | 0.001 | ||||||
BF281741 | glioma tumor suppressor candidate region gene 2 | GItscr2 | 1.18 | 0.067 | 0.84 | 0.068 | 0.93 | 0.461 | ||||||
BM389310 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (predicted) | Ddx41_predicted | 1.18 | 0.096 | 0.77 | 0.021 | 1.33 | 0.019 | ||||||
GROUP 1B | GENES INCREASED IN SBR50 vs. SHAM AND UNCHANGED IN SBR50/IL-6 vs.SBR50 | |||||||||||||
NM_012912 | activating transcription factor 3 | Atf3 | 92.25 | 0.000 | 1.36 | 0.435 | 0.45 | 0.054 | ||||||
NM_031970 | heat shock 27kDa protein 1 | Hspbl | 11.79 | 0.006 | 4.12 | 0.100 | 0.44 | 0.360 | ||||||
NM_053565 | suppressor of cytokine signaling 3 | Socs3 | 10.14 | 0.000 | 0.51 | 0.118 | 1.80 | 0.177 | ||||||
NM_012603 | myeloctomatosis viral oncogene homolog (avain) | Myc | 9.53 | 0.000 | 0.65 | 0.357 | 1.08 | 0.894 | ||||||
BM384926 | DnaJ (Hsp40) homolog, subfamily B, member 1 (predicted) | Dnajb1 | 9.09 | 0.005 | 2.79 | 0.155 | 0.26 | 0.081 | ||||||
NM_013154 | CCAAT CCAAT/enhancer binding protein (C/EBP), delta | Cebpd | 6.32 | 0.000 | 0.60 | 0.151 | 1.38 | 0.387 | ||||||
AF080594 | vascular endothelial growth factor A | Vegfa | 6.14 | 0.000 | 0.60 | 0.188 | 1.04 | 0.923 | ||||||
BG671521 | heat shock protein 1, alpha | Hspca | 4.72 | 0.001 | 1.34 | 0.465 | 0.82 | 0.658 | ||||||
BI284349 | myeloid differentiation primary response gene 116 | Myd116 | 4.65 | 0.004 | 1.71 | 0.270 | 0.98 | 0.969 | ||||||
AF007789 | plasminogen activator, urokinase receptor | Plaur | 4.28 | 0.001 | 0.62 | 0.151 | 1.17 | 0.662 | ||||||
NM_021836 | Jun-B oncogene | Junb | 4.12 | 0.000 | 1.31 | 0.303 | 0.94 | 0.845 | ||||||
NM_022542 | ras homolog gene family, member B | Rhob | 4.06 | 0.001 | 1.19 | 0.629 | 1.05 | 0.900 | ||||||
NM_012551 | early growth response 1 | Egrl | 3.89 | 0.001 | 1.15 | 0.693 | 0.92 | 0.839 | ||||||
NM_058208 | suppressor of cytokine signaling 2 | Socs2 | 3.13 | 0.045 | 0.45 | 0.178 | 1.51 | 0.499 | ||||||
NM_012699 | DnaJ (Hsp40) homolog, subfamily B, member 9 | Dnajb9 | 2.53 | 0.019 | 0.55 | 0.132 | 0.55 | 0.147 | ||||||
NM_013085 | plasminogen activator, urokinase | Plau | 2.23 | 0.085 | 0.81 | 0.690 | 0.87 | 0.791 | ||||||
NM_133416 | B-cell leukemia/lymphoma 2 related protein A1 | Bcl2a1 | 2.22 | 0.048 | 0.81 | 0.630 | 2.78 | 0.028 | ||||||
BM392366 | platelet-activating factor acetylhtdrolase, isoform 1b, alpha2 subunit | Pafah1b2 | 2.13 | 0.007 | 0.84 | 0.511 | 1.26 | 0.398 | ||||||
AI178012 | retinoblastoma 1 | Rb1 | 1.96 | 0.000 | 1.14 | 0.331 | 1.43 | 0.018 | ||||||
BI294137 | Hexokinase 2 | Hk2 | 1.89 | 0.006 | 0.71 | 0.119 | 1.00 | 0.985 | ||||||
AI008680 | benzodiazepine receptor, peripheral | Bzrp | 1.86 | 0.003 | 0.85 | 0.383 | 2.82 | 0.000 | ||||||
NM_017034 | proviral integration site 1 | Pim1 | 1.85 | 0.012 | 0.88 | 0.586 | 1.09 | 0.736 | ||||||
NM_012904 | annexi A1 | Anxa 5 | 1.82 | 0.036 | 0.97 | 0.939 | 0.78 | |||||||
BE109605 | zinc finger protein 162 | Zfp162 | 1.74 | 0.016 | 0.75 | 0.199 | 0.95 | 0.837 | ||||||
NM_013151 | plasminogen activator, tissue | Plat | 1.68 | 0.008 | 0.91 | 0.630 | 1.14 | 0.499 | ||||||
AI178772 | prothymosin alpha | Ptma | 1.67 | 0.010 | 0.86 | 0.424 | 1.42 | 0.084 | ||||||
NM_012734 | hexokinase 1 | Hk1 | 1.67 | 0.012 | 0.73 | 0.116 | 0.86 | 0.459 | ||||||
NM_012523 | CD53 antigen | Cd53 | 1.66 | 0.013 | 0.73 | 0.117 | 1.14 | 0.517 | ||||||
AI237389 | heat shock 90kDa protein 1, beta | Hspcb | 1.64 | 0.032 | 1.30 | 0.258 | 1.49 | 0.106 | ||||||
NM_022531 | Desmin | Des | 1.60 | 0.032 | 0.82 | 0.380 | 1.53 | 0.076 | ||||||
BI296385 | similar to chemokine (C-X-C motif) ligand 16 | Cxcl16 | 1.59 | 0.017 | 0.82 | 0.312 | 1.65 | 0.024 | ||||||
AA945737 | chemokine (C-X-C motif) receptor 4 | Cxcr4 | 1.49 | 0.051 | 0.88 | 0.546 | 1.62 | 0.037 | ||||||
NM_012715 | Adrenomedullin | Adm | 1.48 | 0.057 | 1.12 | 0.605 | 1.76 | 0.020 | ||||||
J04024 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | Atp2a2 | 1.47 | 0.035 | 0.99 | 0.988 | 1.03 | 0.900 | ||||||
NM_024359 | hypoxia inducible factor 1, alpha subunit | Hifla | 1.47 | 0.008 | 0.86 | 0.299 | 1.19 | 0.235 | ||||||
M83297 | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | Ppp2ca | 1.37 | 0.080 | 0.81 | 0.275 | 1.06 | 0.778 | ||||||
BE116857 | apoptotic chormatin condensation inducer 1 | Acin1 | 1.30 | 0.089 | 0.92 | 0.605 | 1.14 | 0.421 | ||||||
AI411586 | Sequestosome 1 | Sqstm1 | 1.29 | 0.040 | 0.94 | 0.673 | 1.21 | 0.153 | ||||||
M25590 | seminal vesicle protein 4 | Svp4 | 1.28 | 0.072 | 0.92 | 0.601 | 0.93 | 0.625 | ||||||
U69550 | phospholipase D1 | Pldl | 1.26 | 0.75 | 0.093 | 0.585 | 0.77 | 0.074 | ||||||
NM_019161 | cadherin 22 | Cdh22 | 1.06 | 0.048 | 0.97 | 0.215 | 0.96 | 0.207 | ||||||
NM_012641 | regenerating islet-derived 1 | Regl | 1.02 | 0.06 | 1.00 | 0.825 | 0.96 | 0.018 | ||||||
BI288701 | B-cell translocation gene 2, anti-proliferative | Btg2 | 25.68 | 0.000 | 0.41 | 0.135 | 1.31 | 0.672 | ||||||
NM_024388 | nuclear receptor subfamily 4, group A, member 1 | Nr4a1 | 9042 | 0.002 | 2.22 | 0.220 | 0.98 | 0.977 | ||||||
NM_024134 | DNA_damage inducible transcript 3 | Ddit3 | 7.53 | 0.002 | 1.21 | 0.757 | 3.78 | 0.033 | ||||||
NM_1335578 | dual specificity phosphatase 5 | Dusp5 | 6.41 | 0.000 | 1.08 | 0.857 | 0.96 | 0.909 | ||||||
NM_013060 | inhibitor of DNA binding 2 | Id2 | 5.69 | 0.000 | 0.69 | 0.201 | 1.77 | 0.063 | ||||||
NM_031628 | nuclear receptor subfamily 4, group A, member 3 | Nr4a3 | 4.96 | 0.036 | 1.34 | 0.726 | 0.68 | 0.653 | ||||||
AI010427 | cyclin-dependent kinase inhibitor 1A | Cdkn1a | 2.90 | 0.013 | 0.55 | 0.151 | 1.83 | 0.171 | ||||||
NM_053847 | mitogen-activated protein kinase kinase kinase 8 | Map3k8 | 2.89 | 0.008 | 0.59 | 0.170 | 1.52 | 0.289 | ||||||
NM_057138 | CASP8 and FADD-like apoptosis regualtor | Cfr | 2.82 | 0.051 | 0.44 | 0.136 | 1.77 | 0.317 | ||||||
NM_053319 | dynein light chain LC8-type 1 | Dynll1 | 2.80 | 0.001 | 1.26 | 0.375 | 1.35 | 0.255 | ||||||
NM_053819 | tissue inhibitor of metalloproteinase 1 | Timp1 | 2.66 | 0.002 | 0.82 | 0.488 | 1.96 | 0.030 | ||||||
NM_194457 | seven in absentia 2 | Siah2 | 2.47 | 0.005 | 0.83 | 0.527 | 0.87 | 0.662 | ||||||
NM_012954 | fos-like antigen 2 /// FBJ asteosarcoma oncogene B | Fos12 | 2.42 | 0.008 | 1.02 | 0.974 | 1.49 | 0.223 | ||||||
NM_012966 | heat shock 10 kDa protein 1 (chaperonin 10) | Hspel | 2.31 | 0.000 | 1.23 | 0.255 | 0.55 | 0.008 | ||||||
BG671549 | superoxide dismutase 2, mitochondrial | Sod2 | 2.27 | 0.077 | 0.57 | 0.238 | 3.76 | 0.018 | ||||||
U05989 | PRKC, apoptosis. WTI, regulator | Paur | 2.06 | 0.003 | 1.35 | 0.165 | 0.99 | 0.976 | ||||||
NM_053957 | amyloid beta (A4) precursor protein-binding, family B, member 3 | Apbb3 | 2.03 | 0.014 | 0.69 | 0.184 | 1.24 | 0.463 | ||||||
NM_017180 | pleckstrin homology-like domain, family A, member 1 | Phidal | 1.96 | 0.051 | 1.09 | 0.844 | 0.98 | 0.968 | ||||||
AB020367 | tribbles homolog 3 (Drosophila) | Trib3 | 1.91 | 0.036 | 0.60 | 0.118 | 1.87 | 0.069 | ||||||
NM_053394 | Kruppel-like factor 5 | Klf5 | 1.85 | 0.062 | 0.62 | 0.165 | 0.86 | 0.680 | ||||||
NM_012953 | fos-like antigen 1 | Fosl1 | 1.84 | 0.061 | 0.65 | 0.204 | 0.82 | 0.595 | ||||||
NM_017258 | B-cell translocation gene 1, anti-proliferative | Btg1 | 1.70 | 0.010 | 0.73 | 0.117 | 1.17 | 0.450 | ||||||
NM_022612 | BCL2-like 11 (apoptosis faciliator) | Bcl2111 | 1.55 | 0.020 | 0.75 | 0.129 | 0.83 | 0.353 | ||||||
AA892271 | BCL2-like 13 (apoptosis faciliator) (predicted) | Bcl2113 | 1.49 | 0.036 | 0.87 | 0.499 | 1.19 | 0.387 | ||||||
AA957342 | peptidylprolyl isomerase D (cyclophilin D) | Ppid | 1.46 | 0.051 | 1.24 | 0.286 | 1.20 | 0.384 | ||||||
NM_053289 | pancreatitis-associated protein | Pap | 1.43 | 0.100 | 0.70 | 0.120 | 1.11 | 0.672 | ||||||
NM_017006 | glucose-6-phosphate dehydrogenase x-linked | G6pdx | 1.41 | 0.005 | 0.89 | 0.293 | 1.83 | 0.000 | ||||||
NM_012829 | Cholecystokinin | Cck | 1.39 | 0.037 | 0.89 | 0.463 | 0.62 | 0.013 | ||||||
AF235993 | Bc12-associated X protein | Box | 1.37 | 0.072 | 1017 | 0.399 | 2.76 | 0.000 | ||||||
NM_019282 | gremlin 1 homolog cysteine knot superfamily (Xenopus laevis) | Grem1 | 1.26 | 0.087 | 0.84 | 0.215 | 0.92 | 0.568 | ||||||
NM_131911 | acidic nuclear phosphoprotein 32 family, member B | Anp32b | 1.23 | 0.025 | 0.86 | 0.117 | 1.18 | 0.095 | ||||||
B1280304 | Bc12-associated athanogene 1 (predicted) | Bag1 | 1.20 | 0.086 | 1.01 | 0.955 | 1.34 | 0.019 | ||||||
BF287444 | glycogen synthase kinase 3 beta | Gsk3b | 1.18 | 0.067 | 0.92 | 0.349 | 1.04 | 0.669 | ||||||
NM_031038 | Gonadotrophin releasing hormone receptor | Gnrhr | 1.15 | 0.050 | 0.89 | 0.113 | 0.97 | 0.736 | ||||||
AF081196 | RAS guanyl releasing protein 1 | Rasgrp1 | 1.10 | 0.018 | 0.94 | 0.140 | 0.94 | 0.154 | ||||||
NM_012650 | sex hormone binding globulin | Shbg | 1.02 | 0.065 | 0.99 | 0.566 | 0.97 | 0.028 | ||||||
GROUP 2A | GENES DECREASED IN SBR50 vs. SHAM AND INCREASED IN SBR50/IL-6 vs. SBR50 | |||||||||||||
NM_052980 | nuclear receptor subfamily 1, group I, member 2 | Nrli2 | 0.09 | 0.000 | 1.38 | 0.027 | 1.39 | 0.031 | ||||||
NM_021745 | nuclear receptor subfamily 1, group H, member 4 | Nrlh4 | 0.40 | 0.002 | 2.99 | 0.003 | 1.35 | 0.251 | ||||||
NM_022407 | aldehyde dehydrogenase family 1, member A1 | Aldhlal | 0.43 | 0.015 | 2.13 | 0.038 | 0.42 | 0.024 | ||||||
NM_012805 | retinoid X receptor alpha | Rxra | 0.49 | 0.000 | 1.27 | 0.084 | 0.81 | 0.130 | ||||||
NM_012493 | alpha-fetoprotein | Afp | 0.50 | 0.007 | 2.02 | 0.012 | 0.86 | 0.547 | ||||||
AI235465 | steroid sensitive gene 1 | Ssgl | 0.50 | 0.012 | 2.07 | 0.015 | 0.53 | 0.030 | ||||||
NM_133400 | apobec-1 complementation factor | Acf | 0.55 | 0.004 | 1.63 | 0.019 | 0.85 | 0.387 | ||||||
BM392373 | CEA-related cell adhestion molecule 1 | Ceacaml | 0.58 | 0.003 | 1.58 | 0.013 | 0.69 | 0.038 | ||||||
BG377107 | DnaJ (Hsp40) homolog, subfamily A, member 3 | Dnaja3 | 0.60 | 0.000 | 1.44 | 0.005 | 0.93 | 0.482 | ||||||
NM_012931 | breast cancer anti-estrogen resistance 1 | Bcarl | 0.60 | 0.018 | 1.65 | 0.027 | 1.25 | 0.310 | ||||||
NM_022614 | inhibin beta C | Inhbc | 0.61 | 0.020 | 1.64 | 0.028 | 0.94 | 0.809 | ||||||
BF282337 | integral membrane protein 2B | Itm2b | 0.63 | 0.000 | 1.27 | 0.007 | 1.13 | 0.117 | ||||||
BI276999 | testis enhanced gene transcript | Tegt | 0.63 | 0.000 | 1.39 | 0.002 | 0.79 | 0.005 | ||||||
AY083159 | Stam binding protein | Stambp | 0.63 | 0.009 | 1.56 | 0.017 | 1.43 | 0.049 | ||||||
BY275921 | anterior pharynx defective la homolog (C. elegans) | Aphla | 0.64 | 0.002 | 1.38 | 0.021 | 2.05 | 0.000 | ||||||
AF347936 | interlekin 11 receptor alpha chain 1 | Ill1rals | 0.65 | 0.009 | 1.60 | 0.011 | 1.27 | 0.154 | ||||||
AW672589 | nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha | Nfkbia | 0.65 | 0.003 | 1.82 | 0.002 | 2.10 | 0.000 | ||||||
BI279735 | Ubiquilin 1 | Frapl | 0.68 | 0.001 | 1.41 | 0.004 | 1.34 | 0.008 | ||||||
NM_017181 | fumarylac etoacetate hydrolase | Fah | 0.69 | 0.002 | 1.29 | 0.002 | 0.75 | 0.019 | ||||||
NM_031546 | Regucalcin | Rgn | 0.69 | 0.004 | 1.57 | 0.004 | 0.31 | 0.000 | ||||||
NM_022277 | caspase 8 | Casp8 | 0.70 | 0.013 | 1.32 | 0.058 | 1.92 | 0.001 | ||||||
AW523747 | adhesion molecule with Ig like domain 2 | Amigo2 | 0.72 | 0.045 | 1.54 | 0.019 | 1.20 | 0.131 | ||||||
BI274345 | ataxin 10 | Atxn10 | 0.73 | 0.008 | 1.22 | 0.079 | 0.90 | 0.387 | ||||||
BI295511 | forkhead box O1A | Foxola | 0.73 | 0.020 | 1.39 | 0.022 | 0.88 | 0.353 | ||||||
AI009817 | succinate dehydrogenase complex, subunit C, integral membrane protein | Sdhc | 0.73 | 0.034 | 1.37 | 0.043 | 1.02 | 0.925 | ||||||
AI011448 | Notch gene homolog 2 (Drosophila) | Notch2 | 0.74 | 0.088 | 1.59 | 0.019 | 1.18 | 0.384 | ||||||
BI285459 | Nicastrin | Ncstn | 0.76 | 0.003 | 1.20 | 0.037 | 1.34 | 0.005 | ||||||
AB015946 | tubulin, gamma 1 | Tubgl | 0.78 | 0.090 | 1.79 | 0.004 | 1.31 | 0.104 | ||||||
NM_022399 | Calreticulin | Calr | 0.80 | 0.016 | 1.31 | 0.012 | 1.05 | 0.595 | ||||||
M15481 | insulin-like growth factor 1 | Igfl | 0.83 | 0.069 | 1.36 | 0.014 | 0.51 | 0.000 | ||||||
NM_024352 | Macrophage stimulating 1 (hepatocyte growth factor-like) | Mstl | 0.83 | 0.038 | 1.28 | 0.017 | 0.84 | 0.077 | ||||||
NM_053491 | Plasminogen | Parl | 0.83 | 0.009 | 1.13 | 0.073 | 0.82 | 0.014 | ||||||
BI281756 | Parkinson disease (auosomal recessive, early onset) 7 | Park7 | 0.85 | 0.036 | 1.35 | 0.004 | 1.13 | 0.166 | ||||||
NM_133317 | transducer of ErbB-2 1 | Tobl | 0.34 | 0.002 | 2.81 | 0.006 | 1.41 | 0.284 | ||||||
AF335281 | STEAP family member 3 | Steap3 | 0.41 | 0.002 | 1.62 | 0.066 | 0.69 | 0.170 | ||||||
AI412114 | etoposide induced 2–4 Mma | Ei24 | 0.46 | 0.000 | 2.14 | 0.002 | 0.98 | 0.917 | ||||||
NM_012870 | retinoblastoma-like 2 | Rb12 | 0.49 | 0.006 | 1.54 | 0.079 | 1.03 | 0.909 | ||||||
NM_012870 | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | Tnfrsf11b | 0.50 | 0.004 | 1.99 | 0.007 | 1.23 | 0.360 | ||||||
NM_0530902 | kynurenimase (L-kynurenime hydrolase) | Kynu | 0.52 | 0.003 | 1.73 | 0.014 | 0.47 | 0.003 | ||||||
AI169638 | sphingosine-l-phosphate phosphatase 1 | Sgppl | 0.53 | 0.002 | 1.51 | 0.028 | 1.47 | 0.048 | ||||||
BM388758 | excision repair cross-complementing rodent repair deficiency, complementation group 3 | Ercc3 | 0.57 | 0.002 | 1.54 | 0.016 | 1.66 | 0.008 | ||||||
BF398331 | estrogen receptor-binding fragment-associated gene 9 | Ebag9 | 0.61 | 0.013 | 1.41 | 0.082 | 0.81 | 0.300 | ||||||
AB004454 | presenilin 2 | Psen 2 | 0.62 | 0.002 | 1.32 | 0.051 | 1.60 | 0.006 | ||||||
NM_019158 | aquaporin 8 | Aqp8 | 0.64 | 0.018 | 1.66 | 0.016 | 0.92 | 0.692 | ||||||
NM_057146 | complement component 9 | C9 | 0.64 | 0.002 | 1.29 | 0.042 | 1.36 | 0.022 | ||||||
AF275151 | androgen receptor-related apoptosis-associated protein CBL27 | Cb127 | 0.65 | 0.001 | 1.36 | 0.011 | 1.03 | 0.772 | ||||||
NM_017319 | protein disulfide isomerase associated 3 | Pdia3 | 0.66 | 0.001 | 1.67 | 0.002 | 1.22 | 0.062 | ||||||
NM_053907 | deoxyribonuclease I-like 3 | Dnase112 | 0.66 | 0.005 | 1.36 | 0.034 | 0.66 | 0.012 | ||||||
AF262320 | programmed cell death 8 | Pdcd8 | 0.69 | 0.000 | 1.19 | 0.009 | 0.92 | 0.164 | ||||||
BM391371 | Goliath | LOC652955 | 0.71 | 0.001 | 1.26 | 0.016 | 0.82 | 0.034 | ||||||
AA819870 | complement component 8, beta polypeptide (mapped) | C8b | 0.79 | 0.018 | 1.28 | 0.024 | 0.80 | 0.038 | ||||||
AI409930 | B-cell receptor-associated protein 31 | Bcap31 | 0.81 | 0.007 | 1.28 | 0.006 | 1.08 | 0.333 | ||||||
GROUP 2B | GENES DECREASED IN SBR50 vs. SHAM AND UNCHANGED IN SBR50/IL-6 vs. SBR50 | |||||||||||||
NM_012842 | epidemal growth factor | Egfr | 0.32 | 0.000 | 1.29 | 0.204 | 0.59 | 0.021 | ||||||
BM385790 | Kruppel-like factor 2 (lung) (predicted) | Klf2 | 0.40 | 0.006 | 1.10 | 0.789 | 1.33 | 0.384 | ||||||
NM_032612 | signal transducer and activator of transcription 1 | Stat1 | 0.45 | 0.075 | 2.20 | 0.101 | 6.09 | 0.003 | ||||||
NM_053923 | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | Pic3c2g | 0.50 | 0.014 | 1.15 | 0.630 | 0.30 | 0.002 | ||||||
NM_031541 | scavenger receptor class B, member 1 | Scarb1 | 0.52 | 0.002 | 1.29 | 0.151 | 0.77 | 0.152 | ||||||
NM_053523 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | Herpud 1 | 0.53 | 0.017 | 1.42 | 0.186 | 0.47 | 0.015 | ||||||
NM_013063 | poly (ADP-ribose) polymerase family, member 1 | Parp12_predicted | 0.56 | 0.011 | 0.87 | 0.539 | 1.02 | 0.951 | ||||||
NM_017206 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | Slc6a6 | 0.56 | 0.078 | 0.81 | 0.539 | 1.60 | 0.185 | ||||||
AA799421 | protein kinase C, epsilon | Prkce | 0.58 | 0.002 | 0.79 | 0.119 | 1.50 | 0.019 | ||||||
NM_022185 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 | Pik3r2 | 0.59 | 0.056 | 1.18 | 0.575 | 1.33 | 0.348 | ||||||
AI177631 | bifunctional apoptosis regualtor | bflar | 0.59 | 0.086 | 0.93 | 0.857 | 1.52 | 0.230 | ||||||
NM_017322 | mitogen-activated protein kinase 9 | Mapk9 | 0.60 | 0.011 | 1.15 | 0.468 | 1.24 | 0.289 | ||||||
NM_017094 | growth hormone receptor | Ghr | 0.61 | 0.072 | 1.15 | 0.650 | 0.60 | 0.096 | ||||||
AI716502 | spkingosine kinase 2 | Sphk2 | 0.64 | 0.046 | 1.44 | 0.119 | 1.06 | 0.837 | ||||||
BG378230 | mitochondrial ribosomal protein S30 (predicted) | Mrps30 | 0.64 | 0.016 | 1.10 | 0.611 | 0.46 | 0.002 | ||||||
NM_019364 | sec 1 family domain containing 1 | Scfd1 | 0.65 | 0.025 | 1.28 | 0.189 | 1.05 | 0.798 | ||||||
BM385237 | annexin A4 | Anxa5 | 0.66 | 0.087 | 1.49 | 0.120 | 2.32 | 0.007 | ||||||
BI289543 | zicn finger, MYND domain containing 11 | Zmynd11 | 0.67 | 0.006 | 1.05 | 0.744 | 1.24 | 0.137 | ||||||
U68544 | peptidylprolyl isomerase F (cyclophilin F) | Ppif | 0.67 | 0.003 | 1.07 | 0.587 | 0.88 | 0.348 | ||||||
NM_031053 | mutL homolog 1 (E. coli) /// hypothetical gene supported by NM_031053 | Mlhl | 0.68 | 0.45 | 1038 | 0.103 | 1.30 | 0.200 | ||||||
X02904 | glutathione-S-transferase, pi 1///glutathione S-transferase, pi 2 | Gstpl | 0.71 | 0.012 | 1.22 | 0.136 | 0.79 | 0.089 | ||||||
NM_053777 | mitogen activated protein kinase 8 interacting protein | Mapk8ip | 0.71 | 0.033 | 1.29 | 0.117 | 0.86 | 0.387 | ||||||
BE110607 | similar to apoptosis related protein APR-3; p18 (predicted) | RGD1311605_predicted | 0.72 | 0.072 | 1.29 | 0.170 | 0.69 | 0.070 | ||||||
NM_012803 | protein C | Sftpc | 0.72 | 0.005 | 1.18 | 0.123 | 0.70 | 0.007 | ||||||
U69109 | protein tyrosine kinase 2 beta | Ptk2b | 0.74 | 0.081 | 1.11 | 0.561 | 1.21 | 0.321 | ||||||
AA819804 | Zinc finger protein 91 | Zfp91 | 0.75 | 0.090 | 1.16 | 0.420 | 1.26 | 0.216 | ||||||
BG673589 | paxillin | Pxn | 0.75 | 0.028 | 1.16 | 0.267 | 1.17 | 0.258 | ||||||
BF419646 | retimoic acid receptor, beta | Ram | 0.75 | 0.086 | 1.14 | D.468 | 2.37 | 0.001 | ||||||
NM_053739 | beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) | Becn1 | 0.75 | 0.037 | 1.17 | 0.258 | 1.11 | 0.470 | ||||||
AI171615 | chromosome segregation 1-like (S. cerevisiae) (predicted) | Csell_predicted | 0.78 | 0.062 | 1.26 | 0.104 | 1.45 | 0.019 | ||||||
NM_053864 | valosin-containing protein | Vcpip1 | 0.78 | 0.010 | 1.06 | 0.501 | 1.14 | 0.176 | ||||||
AIl70385 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | Smarca2 | 0.80 | 0.089 | 1.21 | 0.170 | 0.99 | 0.923 | ||||||
NM_012660 | eukaryotic translation elongation factor 1 alpha 2 | Eefl2a | 0.81 | 0.090 | 1.02 | 0.931 | 0.86 | 0.276 | ||||||
NM_133409 | integrin linked kinase | Ilk | 0.83 | 0.087 | 1.07 | 0.582 | 1.27 | 0.054 | ||||||
AA800669 | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | Ppp2f1a | 0.88 | 0.091 | 1.00 | 0.979 | 1.23 | 0.024 | ||||||
NM_013149 | aryl hydrocarbon receptor | Ahr | 0.32 | 0.001 | 1.21 | 0.502 | 0.92 | 0.776 | ||||||
NM_022180 | hepatocyte nuclear factor 4, alpha | Hrf4a | 0.33 | 0.000 | 1.35 | 0.119 | 1.45 | 0.066 | ||||||
BI297236 | Transformation related protein 53 inducible nuclear protein 1 | Trp53inp1 | 0.49 | 0.053 | 1.47 | 0.317 | 1.06 | 0.894 | ||||||
BE1080508 | Procollagen, type XVIII, alpha 1 | Coll8a1 | 0.49 | 0.045 | 1.56 | 0.217 | 0.67 | 0.283 | ||||||
AB019366 | poly (ADP-ribose) glycohydrolase | Parg | 0.52 | 0.004 | 1.12 | 0.611 | 1.49 | 0.072 | ||||||
NM_012498 | aldo-keto reductase family 1,member B4 (aldose reductase) | Akr1b4 | 053 | 0.003 | 1.33 | 0.138 | 1.10 | 0.660 | ||||||
NM_053307 | methionine sulfoxide reductase A | Msra | 0.60 | 0.002 | 1.26 | 0.125 | 0.47 | 0.001 | ||||||
BF400782 | protein kinase, DNA activated, catalytic polypeptide (predicted) | Prkdc_predicted | 0.60 | 0.005 | 1.06 | 0.733 | 0.89 | 0.506 | ||||||
NM_017079 | CDldl antigen | Cdldl | 0.60 | 0.031 | 1.46 | 0.118 | 1.28 | 0.317 | ||||||
NM_053448 | histone deacetylase 3 | Hdac3 | 0.61 | 0.028 | 1.39 | 0.147 | 1.24 | 0.367 | ||||||
A1408078 | BCL2-associated transcription factor 1 | Bclaf1 | 0.64 | 0.028 | 0.93 | 0.748 | 0.72 | 0.130 | ||||||
BF283688 | tumor necrosis factor ligand superfamily member 12 | Tnflfl2 | 0.65 | 0.069 | 1.46 | 0.123 | 1.19 | 0.497 | ||||||
B1286396 | PERP, TP53 apoptosis affector (predicted) | Perp | 0.69 | 0.042 | 1.13 | 0.540 | 0.51 | 0.005 | ||||||
BE107162 | high mobility group box 1 | Hmgb1 | 0.69 | 0.005 | 1.17 | 0.199 | 0.89 | 0.374 | ||||||
BF408447 | programmed cell death 5 (predicted) | Pdcd8 | 0.70 | 0.013 | 1.25 | 0.123 | 1.19 | 0.236 | ||||||
U06230 | protein S (alpha) | Prosl | 0.70 | 0.019 | 1.14 | 0.405 | 0.70 | 0.034 | ||||||
A1227743 | Fas-activated serine/threonine kinase | Fastk | 0.72 | 0.017 | 1.00 | 0.989 | 1.11 | 0.459 | ||||||
AIl76519 | immediate early response 3 | Ier3 | 0.73 | 0.051 | 1.32 | 0.110 | 1.16 | 0.396 | ||||||
NM_130406 | Fas-associated factor 1 | Fafl | 0.74 | 0.061 | 1.16 | 0.389 | 1.51 | 0.030 | ||||||
BM389034 | TNF receptor-associated protein 1 | Trap 1 | 0.74 | 0.036 | 1.08 | 0.636 | 0.91 | 0.554 | ||||||
AA800180 | thioredoxin 2 | Txn2 | 0.75 | 0.029 | 1.10 | 0.465 | 1.18 | 0.230 | ||||||
D14592 | mitogen activated protein kinase kinase 2 | Map2k2 | 0.75 | 0.033 | 1.23 | 0.132 | 1.37 | 0.037 | ||||||
BG665132 | mitochondrial carrier homolog 1 (C. elegans) | Mtch1 | 0.77 | 0.022 | 1.08 | 0.537 | 1.17 | 0.207 | ||||||
BM390196 | thioredoxin domain containig 5 (predicted) | Txndc5_predicted | 0.77 | 0.043 | 1.22 | 0.126 | 0.65 | 0.008 | ||||||
BF284481 | SH3-domain GRB2-like B1 (endophilin) | Sh3glbl | 0.77 | 0.087 | 0.93 | 0.673 | 1.23 | 0.213 | ||||||
BM383722 | NCK-assocaited protein 1 | Nell1 | 0.80 | 0.070 | 1.06 | 0.646 | 0.95 | 0.719 | ||||||
NM_031978 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | Psmd1 | 0.81 | 0.093 | 1.14 | 0.336 | 1.33 | 0.052 | ||||||
AA946474 | Calpastatin | Cast | 0.82 | 0.089 | 0.96 | 0.781 | 1.15 | 0.288 | ||||||
GROUP 3 | GENES INCREASED IN SBR50 vs. SHAM AND INCREASED IN SBR50/IL-6 vs. SBR50 | |||||||||||||
B1278231 | heat shock 70kD protein 1B (mapped) | Hspalb | 51.80 | 0.002 | 7.75 | 0.072 | 0.06 | 0.026 | ||||||
NM_031971 | heat shock 70kD protein 1A /// heat shock 70kD protein 1B (mapped) | Hspala | 45.41 | 0.002 | 7.32 | 0.061 | 0.08 | 0.026 | ||||||
AI236601 | heat shock 105kDa/110kDa protein 1 | Hsph1 | 8.49 | 0.006 | 3.36 | 0.097 | 0.43 | 0.264 | ||||||
B1288619 | Jun oncogene | Jun | 5.64 | 0.001 | 2.68 | 0.021 | 0.51 | 0.102 | ||||||
NM_031327 | cysteine rich protein 61 | Cyr61 | 3.48 | 0.003 | 4.43 | 0.004 | 0.52 | 0.105 | ||||||
AA818262 | angiopoietin-like 4 | Angpt14 | 2.98 | 0.000 | 1.50 | 0.028 | 1.37 | 0.089 | ||||||
NM_012935 | crystallin, alpha B | Cryab | 1.82 | 0.016 | 1.84 | 0.021 | 0.88 | 0.619 | ||||||
AF077354 | heat shock protein 4 | Hspa4 | 1.50 | 0.037 | l.46 | 0.063 | 1.20 | 0.381 | ||||||
A1599423 | growth arrest and DNA-damage-inducible 45 gamma | Gadd45g | 8.66 | 0.000 | 2.50 | 0.005 | 0.80 | 0.411 | ||||||
A1231792 | Bc12-associated athanogene 3 | Bag3 | 3.76 | 0.018 | 3.16 | 0.049 | 0.16 | 0.007 |
Genes listed in regular type are anti-apoptotic, while genes listed in italics are pro-apoptotic.
FDR: False discovery rate.