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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Microb Pathog. 2008 Jul 4;45(4):282–289. doi: 10.1016/j.micpath.2008.06.003

Table 3. Arginine 362 has a role in IpaC effector function.

Mutant Relative invasiona
Wild-type 100 ± 12
R362W 3 ± 1
R362K 118 ± 17
R362M 66 ± 9
R362E 32 ± 5
a

Invasion was tested using a standard gentamycin protection assay with SF621 complemented with wild-type ipaC serving as the positive control. Invasiveness by the positive control was 132± 16 bacteria per well. (n=3)