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. 2008 Sep 5;17(23):3806–3813. doi: 10.1093/hmg/ddn278

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Published by Oxford University Press 2008

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Figure 3. — Maternal–fetal cholesterol transfer. (A) ¹⁴C-cholesterol transfer from mother to fetus in Abca1 pregnancies. Abca1^+/+, n = 6, Abca1⁺^/−, n = 11, and Abca1⁻^/−, n = 10, from four litters; *P < 0.0001, unpaired t-test. (B) ¹⁴C-cholesterol transfer from mother to fetus in Abcg1 pregnancies. Abcg1⁺^/⁺, n = 8, Abga1⁺^/−, n = 11 and Abcg1⁻^/−, n = 7; from three litters; P = 0.08, unpaired t-test. (C) ¹⁴C-cholesterol transfer from mother to fetus in Sr-b1 pregnancies. Sr-b1^+/+, n = 6, Sr-b1^+/−, n = 11 and Sr-b1^−/−, n = 5, from four litters (Sr-b1^−/− in two litters); *P < 0.003, unpaired t-test. Values are percent of mean of +/+ and +/− within each litter. +/+ and +/− did not differ significantly for any of the genotypes.