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. 2008 Sep 5;17(23):3806–3813. doi: 10.1093/hmg/ddn278

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Published by Oxford University Press 2008

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Figure 5. — Increased cholesterol content in Dhcr7^−/− fetuses by maternal LXR-agonist treatment. Placental gene expression in Dhcr7-mice treated with LXR-agonist. Fold change in mRNA expression compared with the mean control value. Mutant controls: n = 11; mutant TO901317 treated: n = 11. (A) *Abca1, P = 0.0003. (B) *Abcg1, P < 0.0001, both unpaired t-test. (C) The effect of LXR-agonist treatment on cholesterol content of Dhcr7^−/− fetuses. Mutant controls: n = 7; mutant TO901317 treated: n = 7; *P = 0.001, unpaired t-test.