Figure 5. Death-related down-regulated expression changes in WR99210-treated parasites.

Genes whose expression changed in dying cells but not in three other controls were identified. Expression levels were compared between SD and SS, SD and RD, and SD and RS at each time point. Probes were selected against these three comparisons jointly, with multiple testing adjusted p<0.01. Twenty one genes showed a drug-dependent decrease in gene expression (see Table S5 for PlasmoDB gene number).