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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: J Cereb Blood Flow Metab. 2007 May 16;28(1):90–98. doi: 10.1038/sj.jcbfm.9600509

Figure 5. IL-6 attracts EPC migration.

Figure 5

A. Bar graph shows that IL-6-stimulated EPCs to migrate across a porous filter judged by Boyden chamber assays. IL-6 induced EPC migration in a dose-dependent manner. B. Bar graph shows that IL-6 significantly increased EPC migration compared to the negative control. This action was attenuated using IL-6 antibody (50 ng/ml) neutralizing or IL-6 receptor antibody (2 μg/ml) inhibition. VEGF (20 ng/ml) acted as a positive control and PBS as a negative control. Each experiment was performed three times. The results are mean±SD, n=3, *=p<0.01, IL-6 treated group vs. the control; #=p<0.05, IL-6 antibody treated group vs. IL-6 plus antibody treated or IL-6 receptor treated groups.