Figure 4.
Alveolar bone loss is significantly greater in the periostin-null mice compared to control mice. A) Micro-CT qualitative assessment of interradicular alveolar bone defects. B) Histology confirms the altered integrity of the periodontal structures (hematoxylin and eosin; original magnification, ×4.) C and D) Linear quantitation of the interproximal alveolar bone from the cemento-enamel junction (CEJ) to the most coronal aspect of the alveolar crest reflects significant differences in the absence of periostin protein. *P <0.05.