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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: J Periodontol. 2008 Aug;79(8):1480–1490. doi: 10.1902/jop.2008.070624

Figure 5.

Figure 5

Cyst formation in the ameloblast layer and detached cementoblasts in the periostin-null peridontium. A) The wild-type adult mice present a well-organized ameloblast layer composed of polarized cylindrical simple epithelium. B) The periostin knock-out mice display a disorganized pseudostratified epithelial layer that is poorly attached and appears to produce an amorphous matrix that covers the dentin and that is also present ectopically within this matrix-producing organ. C and E) Normal attachment and distribution of cementoblasts at the root surface (arrow) in the wild-type control. D and F) Periostin-null periodontium. Notice the absence of cementoblasts and an apparent disengagement of the PDL from the root surface. Note the absence of cementoblasts attached to the root surface (arrow). (H&E staining: A and B; TRAP and hematoxylin staining: C, D, E, and F; original magnification: A and B, ×20; C and D, ×10; E and F, ×40.)