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. Author manuscript; available in PMC: 2008 Nov 7.
Published in final edited form as: J Neurochem. 1995 Oct;65(4):1481–1486. doi: 10.1046/j.1471-4159.1995.65041481.x

FIG. 6.

FIG. 6

Dynorphins stimulate [3H]thymidine incorporation into 21-day fetal rat brain cell aggregates. Aggregates were prepared from embryonic day 15 fetal rat brain and grown as described in Materials and Methods. Medium was replenished by 50% on every third day of culture. Dynorphins (1 μM) were added after 19 days together with protease inhibitors, and [3H]thymidine was present for the last 24 h. Control values for thymidine incorporation were 16 fmol/dish. Data are the mean ± SEM values of three experiments. *Significantly different from controls and nor-BNI–treated aggregates, p < 0.05.