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Mutational effects on hTgs1 activity
| hTGS1-(631–853) allele | Methyltransferase (% of wild type) | Complementation of tgs1Δ mud2Δ |
|---|---|---|
| Wild type | 100 | +++ |
| F655A | <1 | – |
| T673A | 13 | + |
| D696A | <1 | – |
| N704A | 5 | – |
| D719A | <1 | – |
| N731A | 4 | – |
| S763A | 26 | ++ |
| W766A | <1 | – |
| R807A | 6 | – |
| N808A | 11 | ± |
