FIGURE 8.

Comparative structure modeling of mutant peptides based on the crystal structure of human RLN2. Three-dimensional structure of the wild type human RLN2 and the K^A17A mutant based on the RLN2 crystal structure (PDB 6RLN). The wild type RLN2 structure is shown on the left and right panels. The K^A17A mutant is shown on the middle panel. The A and B chains are indicted by white filled space and green dot space, respectively. The amino acids at A16, A17, and A23 positions are indicated by the brown filled space. The Arg^B12, Arg^B16, and Ile^B19 residues in the RXXXRXXI motif of B chain are represented by the blue filled space.