TABLE 5.

Compilation of mutations at A/T and G/C sites caused by error-prone MMR

	Estimated mutation frequency per site × 10–6a
	Tonsil B-cells	Ramos	HeLa
A/T mutations	57	40	1
G/C mutations	65	119	247

^aMutation frequency per site for A/T and G/C mutations was calculated from Table 4 by subtracting the background mutation frequency (no lysate, Table 4). Since there are two A/T sites in the TGA codon, the frequency per site for A/T mutations was obtained by dividing by 2