Skip to main content
. Author manuscript; available in PMC: 2008 Nov 8.
Published in final edited form as: Mol Ther. 2005 Feb;11(2):245–256. doi: 10.1016/j.ymthe.2004.09.013

FIG. 7.

FIG. 7

AAV-mediated ΔR4/ΔC microdystrophin expression did not compromise contractile properties of the normal EDL muscle. The left EDL muscles of 4.5-month-old mdx mice were infected with AV.ΔR4/ΔC. The contralateral right EDL muscles served as sham-infected controls. Muscle contractile assays were performed when mice were 9 months of age. (A) Force–frequency relationship between sham-infected (open bar) and AV.ΔR4/ΔC-infected (filled bar) EDL muscles. No statistically significant difference was seen between the two groups ( P > 0.05). (B) Relative tetanic force drop during 10 cycles of eccentric contraction. Open circles, sham-infected EDL muscles (mean − SEM); closed circles, EDL muscles infected with AV.ΔR4/ΔC (mean + SEM). N = 3 pairs. There was no statistical difference between AV.ΔR4/ΔC-infected and sham-infected groups ( P > 0.05).