TABLE 1.
EDL characteristics at harvest | |||||||
---|---|---|---|---|---|---|---|
Strain | AV.RSV.AP | Na | Age at infection | Age at harvest | Weight (mg) | CSA (mm2)b | Transduction (%) |
BL10 | No | 4 | N/Ac | 77 days | 8.00 ± 0.29 | 1.51 ± 0.05 | N/Ac |
BL10 | Yes | 4 | 43 days | 77 days | 8.30 ± 0.16 | 1.56 ± 0.04 | 56.75 ± 5.88d |
mdx | No | 5 | N/Ac | 74 days | 11.34 ± 0.33 | 2.05 ± 0.06 | N/Ac |
mdx | Yes | 5 | 42 days | 74 days | 11.36 ± 0.16 | 2.02 ± 0.07 | 53.60 ± 3.88d |
Study was performed in paired legs. The left EDL muscle was infected with AV.RSV.AP, the right EDL muscle of the same mouse was not infected with AAV.
Cross-sectional area (calculated according to fiber length).
Not applicable.
There was no statistical difference in transduction efficiency between BL10 and mdx.