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(a) A dose-response of PS-501 on hydroxyl radical generation from MG. Control: without PS-501. Hydroxyl radicals were generated from MG (10 mg/assay). Sweep time: 2 min; accumulation: ×4 times. (b) Inhibitory effect of PS-501 on hydroxyl radical generation from MG. The relative peak height of the second peak of DMPO-OH spin adducts was plotted against the concentration of MG. The intensity of the DMPO-OH spin adducts were normalized by an internal standard, MnO.
