Table 1.
Demographic, Clinical, and Neuropsychological Characteristics of Sample
| Mean (SD) |
||||
|---|---|---|---|---|
| Characteristic | Normal (CDR=0) |
All (CDR=0.5) |
vMCI | MCI |
| Sample size | 77 | 167 | 125 | 42 |
| Age, y | 71.6 (4.5) | 72.7 (5.8) | 72.3 (5.6) | 73.8 (6.2) |
| Education, y | 15.4 (2.8) | 15.3 (2.9) | 15.3 (3.0) | 15.1 (2.6) |
| Sex, M/F | 30/47 | 75/92 | 57/68 | 18/24 |
| CDR sum of boxes | 0.01 (0.08) | 1.33 (0.78)a | 1.23 (0.70)b,c | 1.61 (0.93)a,d |
| MMSE23 score | 29.5 (0.7) | 29.1 (1.6) | 29.2 (0.7) | 28.6 (0.9) |
| CVLT24 total learning score | 0.13 (0.99) | −0.39 (1.03)a | −0.16 (0.80) | −1.50 (0.82)a,d |
| CVLT delayed retention scoree | −0.08 (0.98) | −0.18 (1.28) | 0.32 (0.86)b,c | −1.66 (1.18)a,d |
| Free and Cued Selective Reminding Test27 score | 0.07 (1.05) | −0.20 (1.25) | 0.08 (1.02) | −1.05 (1.47)a,d |
| Trails B28 score | −0.07 (0.99) | −0.18 (1.22) | −0.12 (1.13) | −0.35 (1.45) |
| Self-Ordering Test29 score | −0.07 (1.06) | −0.49 (1.05)c | −0.37 (0.97)b,f | −0.85 (1.22)c,d |
Abbreviations: CDR, Clinical Dementia Rating; CVLT, California Verbal Learning Test; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; Trails B, Trail Making Test Part B; vMCI, very mild cognitive impairment.
a
P<.001.
b
Different from normal group.
c
P<.005.
d
Different from vMCI group.
e
CVLT delayed free recall/CVLT last immediate learning trial.
f
P<.05.