. Author manuscript; available in PMC: 2008 Dec 1.

Published in final edited form as: Arch Gen Psychiatry. 2007 Dec;64(12):1443–1450. doi: 10.1001/archpsyc.64.12.1443

Table 2.

Adjusted Univariate Analyses of Baseline Clinical and Neuropsychological Measures Predicting Probable AD Diagnosis or Subsequent Cognitive Decline (CDR-SB Increase ≥ 1.0) Over Approximately 5-Year Follow-up Period^a

	OR (95% CI)
	Probable AD Diagnosis Over 5 Years		Clinically Significant Cognitive Decline Over 5 Years
	Entire Sample	vMCI	Entire Sample	vMCI
CDR-SB	4.8 (3.0-7.8)^b	1.65 (1.2-2.1)^c	2.25 (1.61-3.15)^b	1.93 (1.5-2.6)^c
CVLT²⁴ total learning score	0.62 (0.45-0.87)^c	1.2 (0.67-2.2)	0.76 (0.59-0.99)^d	1.4 (0.89-2.3)
CVLT delayed retention score	0.61 (0.46-0.81)^c	0.76 (0.44-1.3)	0.78 (0.62-0.98)^d	0.81 (0.52-1.3)
Free and Cued Selective Reminding Test²⁷ score	0.57 (0.42-0.76)^b	0.78 (0.50-1.2)	0.64 (0.50-0.82)^b	0.66 (0.45-0.97)^d
Trails B²⁸ score	0.57 (0.42-0.79)^c	0.52 (0.33-0.84)^c	0.76 (0.59-0.97)^d	0.74 (0.51-1.1)
Self-Ordering Test²⁹ score	0.60 (0.43-0.83)^c	0.76 (0.47-1.2)	0.68 (0.52-0.88)^c	0.93 (0.63-1.4)

Abbreviations: AD, Alzheimer disease; CDR-SB, Clinical Dementia Rating sum of boxes; CI, confidence interval; CVLT, California Verbal Learning Test; OR, odds ratio; Trails B, Trail Making Test Part B; vMCI, very mild cognitive impairment.

Adjusted for age, sex, and education.

P<.001.

P<.005.

P<.05.