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. Author manuscript; available in PMC: 2008 Nov 10.
Published in final edited form as: J Vestib Res. 2008;18(1):59–68.

Table 4.

Pseudo-haplotype analysis of glutathione S-transferase genes (GSTZ1, GSTM2, GSTP1) showing pseudo-haplotypes with a frequency of at least 5% in either cases or controls

Pseudo-
Haplotype1
Frequency
in cases
Frequency
in controls
Odds ratio 95% C.I. Chi Square
p-values
G-G-A-A-C 0.1995 0.2443 0.657 0.426 ∼ 1.013  0.056
G-G-A-A-T 0.1706 0.0744 2.377 1.335 ∼ 4.231  0.003
G-G-A-G-T 0.0802 0.1268 0.528 0.295 ∼ 0.945  0.030
G-A-A-G-C 0.0753 0.0231 3.166 1.234 ∼ 8.119  0.012
A-A-A-A-C 0.0689 0.00005 1.369 0 ∼ 52823 < 0.001
G-G-A-G-C 0.0683 0.0497 1.272 0.605 ∼ 2.677  0.525
G-A-A-A-C 0.0579 0.0977 0.503 0.2587 ∼ 0.977  0.040
A-A-A-G-T 0.0511 0.0384 1.224 0.526 ∼ 2.845  0.639
G-G-B-A-C 0.0304 0.0746 0.346 0.149 ∼ 0.801  0.010
1

Alleles are shown in order for the following polymorphisms: GSTZ1 p.Arg42Gly, GSTZ1 p.Lys32Glu, GSTM3 c.468+21_22insAGG (A, insertion; B, deletion), GSTP1 p.Ile105Val, GSTP1 p.Ala114Val. The overall analysis showed a significant association (p = 0.002).