Figure 4. Characterization of hepatic markers expression in hESC differentiated with NaB.
cDNA macroarray results of gene expression analysis in undifferentiated (undiff) HES1 and HES2 cells or cells treated with NaB for 7 or 14d, or with the basic medium only (con). The same RNA samples that were utilized for miRNA profiling were used for this analysis. The average results of two independent experiments are presented as gene expression level in arbitrary units. CK8-cytokeratin 8; CK18–cytokeratin 18; CK19–cytokeratin 19; AFP-alpha-fetoprotein; TTR-transthyretin; ALB–albumin; ASGR1-asialoglycoprotein receptor 1; TDO2-tryptophan 2,3 dioxygenase; DLK1-Delta-like 1 Homolog.
