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Effects of NPY agonists on TRH-induced changes in [Ca 2+]i and PRL secretion from cultured AP cells from lactating rats.
| Inhibition of TRH-Induced | |||
|---|---|---|---|
| Agonist | Active at NPY receptor(s) | [Ca 2+]i | PRL Release |
|
| |||
| [Pro34] NPY | Y1, Y2, Y4 | YES | YES |
| [Pro34] PYY | Y1, Y4, Y5 | YES | YES |
| [Leu31, Pro34] NPY | Y1, Y4, Y5 | YES | YES |
| [Leu31, Pro34] PYY | Y1, Y4, Y5 | YES | YES |
| NPY3-36 | Y2, Y5 | YES | YES |
| PYY3-36 | Y2, Y5 | YES | YES |
| NPY13-36 | Y1, Y2, Y4, Y5 | YES | YES |
| hPP | Y1, Y4, Y5 | YES | YES |
| C2-NPY | Y2 | NO | NO |
