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. Author manuscript; available in PMC: 2008 Nov 10.
Published in final edited form as: Cell Cycle. 2008 Mar 18;7(10):1490–1495. doi: 10.4161/cc.7.10.5963

Figure 4.

Figure 4

Correlation between activation of ATM and Chk2 during A549 cells in response to oxidative stress. Bivariate (ATM-S1981P vs Chk2-Thr68P IF) distributions of cells treated with 200 μM H2O2 for 10 min or 1 h. (A–C) show all cells, (D–F) show S-phase cells gated based on differences in DNA content as described in Materials and Methods. The dashed horizontal or vertical lines show the upper thresholds values of Chk2-Thr69P IF or ATM-Ser1981P IF for 97% cells from the untreated (time 0) culture, respectively.