Table 1.

The HLA Bw4 and Bw6 motifs and alleles

		Amino-acid position				Corresponding alleles
		80	81	82	83
Bw4 isoleucine	Ile80	Ile	Ala	Leu	Arg	B*15 (13, 16, 17. 23, 24) B*2702, B*3801, B*4901, B*51, B*5201, B*5301, B*5302, B*57, B*58, B*59
threonine	Thr80	Thr	Ala	Leu	Arg	B*13 (01, 02, 04), B*3802, B*44 (02, 03, 04, 05, 08, 21)
		Thr	Leu	Leu	Arg	B*2705, B*2709, B*3701, B*4701
Bw6 asparginine	Asn 80	Asp	Lau	Arg	Gly	B*07 (02, 03, 04, 05, 08, 09, 10, 14) B*08, B*14.
						B15*(01, 03, 04, 09, 15, 18, 22, 37 45, 48, 13, 16, 17, 23, 24)) B*18, B*35, B*39, B*40, B*41, B*42, B*4501, B*4601, B*48, B*50, B*5401, B*55, B*56, B*67, B*73, B*7801, B*8101, B*82

In bold are alleles whose leader peptide has methionine in the second position and the rest have threonine in the second position [50].