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. 2008 Sep 26;9(11):1141–1148. doi: 10.1038/embor.2008.174

Figure 2.

Figure 2

Development of myeloid lineages from CNB1-deficient bone marrow. (A) Percentage of indicated cellular subsets in bone marrow and spleen of mice transplanted with control or CNB1-deficient bone marrow. Mice were analysed by using flow cytometry 4 months after transplantation. (B) Absolute numbers of CD45.2+ cells of the indicated phenotype in bone marrow of transplanted recipients. (C) Absolute numbers of CD45.2+ cells of the indicated phenotype in the spleen of transplanted recipients. (D) Genomic PCR of the Cnb1 locus in tissues isolated from transplanted mice. (E) Immunoblot analysis of CNB1 and CNB2 protein expression in tissues isolated from transplanted mice. (F) Relative ratio of CD45.2+ to CD45.1+ cells in mice transplanted with CD45.2+ control or CNB1-deficient bone marrow mixed at a 1:1 ratio with B6.SJL bone marrow. Each symbol represents an individual animal. Bars represent mean values. The grey line indicates the predicted 1:1 ratio (logarithm of 1:1 equals 0). BM, bone marrow; Sp, spleen; Thy, thymus.