Skip to main content
. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: J Pediatr. 2008 Mar 6;153(1):105–111. doi: 10.1016/j.jpeds.2008.01.001

Table 3.

Adjusted Effects of Drug, Alcohol, IDA, and Lead Exposures on Child Outcomes (n = 293)*

Cocaine Prenatal Alcohol Marijuana IDA Postnatal Lead HOME
WISC-IV Subscale
Verbal Comprehension IQ β= −0.11, p < .07 β= −0.14, p < .02 β= −0.17, p < .004
  Similarities β= −0.12, p < .05 β= −0.18, p < .003
  Vocabulary 3rd tri. β= −0.12, p < .05 β= −0.18, p < .002 β= −0.13, p < .03
  Comprehension β= 0.15, p < .01
Perceptual Reasoning IQ β= −0.16, p < .02 β= −0.16, p < .007
  Block design β= −0.17, p < .005 β= −0.12, p < .06
  Picture concept β= −0.14, p < .03
  Matrix reasoning β= −0.11, p < .07 β= −0.18, p < .003
Working Memory IQ Average β= −0.14, p < .04 β= 0.16, p < .01
  Digit span 3rd tri. β= −0.13, p < .04 β= −0.10, p < .09
  Letter-number sequencing Average β= −0.18, p < .007 β= −0.11, p < .07 β= 0.17, p < .004
Process Speed IQ β= 0.15, p < .02
  Coding 3rd tri. β= −0.22, p < .0005 β= −0.11, p < .07
  Symbol search β= 0.11, p < .06
Full-scale IQ 3rd tri. β= −0.11, p < .08 β= −0.14, p < .02 β= 0.16, p < .007
Full-scale IQ > 100 O.R. =.51 (0.24 – 1.11), p < .09 O.R.= .43 (0.22 – 0.85), p < .02 O.R.=1.07 (1.00 – 1.14), p < .05
Woodcock-Johnson Subscale
Reading Summary Score 3rd tri. β= −0.17, p < .008 β= −0.10, p < .08 β= −0.15, p < .01 β= 0.14, p < .02
  Letter-word β= −0.15, p < .01 β= 0.13, p < .03
  Identification Passage comprehension β= −0.18, p < .003 β= 0.10, p < .08
  Reading fluency β= −0.15, p < .02 β= 0.11, p < .07
Math Summary Score β= −0.12, p < .04
  Calculation β= −0.12, p < .04
  Applied problems β= −0.10, p < .10 β= −0.12, p < .04
  Math fluency β= −0.11, p < .07 β= 0.15, p < .02
*

Since the impact of combined cocaine- adoptive/foster care effect was mediated completely by lead exposure, the β’s were estimated based on the model without the combined cocaine- adoptive/foster care variable.

There were several positive correlations of first trimester marijuana exposure on outcomes (β’s = .13, p’s < .05 for similarities, vocabulary, and picture concepts). However, since only 1 child was exposed only to marijuana during the first trimester, these were deleted.