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Loss of yKu70 function results in expression of the HMR∷URA3pr-ADE2 reporter gene as revealed by growth on media lacking adenine. Strains shown are DRY640 (HMRa ade2-1), DRY707 (HMRa ADE2), DRY1667 (HMR∷URA3pr-ADE2), DRY1665 (HMR∷URA3pr-ADE2 ΔI), DRY5404 (HMR∷URA3pr-ADE2 yku70Δ), and DRY5402 (HMR∷URA3pr-ADE2 sir1Δ).
