Figure 4.—
yKu70 is recruited to HMR and HML silencer regions in a Sir4-dependent manner as revealed by chromatin immunoprecipitation and real-time quantitative PCR. Fold enrichment values are normalized to the 7.5 TEL on chromosome 6R for the wild-type strain DRY3762 (darkly shaded bar) and the sir4Δ strain DRY5539 (lightly shaded bar).