TABLE 1.
MraY protein | Position of E-resistance mutation | Protection at A550 = 0.2 | Protection at A550 = 0.5 | Apparent affinity for E |
---|---|---|---|---|
MraY | No | Yes | +++ | |
MraYD267N | No | Yes | ||
BsMraY | Yes | Yes | −/+ | |
BsMraYD231N | No | No | ||
MraYG186S | TMD5 | No | Yes | +++ |
MraYG186S, D267N | No | Yes | ||
MraYV291M | TMD9 | No | Yes | +++ |
MraYD267N, V291M | No | Yes | ||
MraYΔL172 | TMD5 | No | Yes | + |
MraYΔL172, D267N | No | No | ||
MraYP170L | TMD5 | No | Yes | + |
MraYP170L, D267N | No | No | ||
MraYF288L | TMD9 | Yes | Yes | −/+ |
MraYD267N, F288L | No | No |