TABLE 2.

Sequence analysis of Htg QTL

QTL (chromosome)	QTL coordinatesa	Size (bp)	No. of genesb	Total SNPsc	No. of nonsynonymous SNPs	No. of genes with coding differences
Htg-QTL-2 (XIV)	395,662–410,654	14,992	8	71	14	6
Htg-QTL-3 (XV)	921,238–965,555d	44,317	16	84	22	10
Htg-QTL-4 (IV)	1,325,183–1,385,259e	60,076	28	320	43	17

^aCoordinates of the highest linkage peak relative to S288c sequence.

^bConfirmed ORFs within QTL coordinates, according to SGD annotations (http://www.yeastgenome.org/).

^cSequence polymorphisms, including nucleotide substitutions, insertions and deletions, between YJM421 and S288c.

^dHtg-QTL-3 coordinates are based on linkage data from F₁-14d/S288c and F₁-50b/S288c segregants (see Figure 3).

^eCoordinates from 1,325,183–1,330,000 bp, 1,352,288–1,353,000 bp, and 1,384,924–1,385,259 bp relative to S288c sequence were not sequenced.