TABLE 4.
Insertion sites and putative identities of resistant Drosophila lines
| Line | Insertion site | Closest gene | Function | Anopheles homolog |
|---|---|---|---|---|
| EP2425 | 2R: 2551842a | tsp42ej | Signaling | |
| 11603 | 3L: 13424707a | CG10133 | Phospholipase A2 | ENSANGG00000007839 |
| 12718 | 3R: 10902878 | CG12601 | Unknown | ENSANGG00000016829 |
| 12738 | X: 10660983 | CG1691 | mRNA binding | ENSANGG00000014401 |
| 12516 | X: 6478974 | CG3168 | Transporter | ENSANGG00000010074 |
| 13425 | 3R: 3645219a | CG31473 | Pyridoxamine-phosphate oxidase | |
| 13462 | X: 11636313 | Hsc70-3 | Heat-shock protein | ENSANGG00000010404 |
| 13593 | X: 2439599 | trol | Unknown | ENSANGG00000017722 |
| 13596 | X: 14436517a | CG9413 | Amino acid permease | ENSANGG00000017734 |
| 13739 | X: 2760775 | CG11086 | Unknown | ENSANGG00000019046 |
| 13760 | X: 1129267 | l(3)82Fd | lysM domain: peptidoglycan-binding hydrolase | ENSANGG00000006384 |
| 13918 | 2L: 6252967 | CG9486 | N-acetyltransferase | |
| 13995 | 2L: 7782431 | CG7164 | Unknown | |
| 16497 | 3L: 9031537a | ArgK | Arginine kinase | ENSANGG00000019341 |
The insertion sites for the P. gallinaceum-resistant mutants as recorded by FlyBase or the P screen database are shown. The identity of the strongest mosquito homolog for each putative mutant is listed in the last column.
a
The insertion site for these lines were confirmed by inverse PCR.