Mean squared error (MSE) of the quantitative trait locus effect estimation, as a function of the variance and squared bias of the estimator averaged over the replicates for the different selective profiling strategies and samples sizes, from bivariate (A, C, and E) and univariate analysis methods (B, D, and F), for the high- (A and B), low- (C and D), and medium- (E and F) correlation scenarios. The full-panel MSE corresponding to a sample size of 510 animals is plotted for reference.