Table 1.
Immunohistologic analysis of PTP1B protein expression in hematolymphoid neoplasia
| Lymphoma subtype | Total positive* | % positive |
|---|---|---|
| B-cell lymphoma (N = 339) | ||
| Follicular lymphoma | ||
| Grade 1 | 0/48 | 0 |
| Grade 2 | 8/59 | 14 |
| Grade 3 | 20/68 | 29 |
| Diffuse large B-cell lymphoma | 46/80 | 58 |
| Burkitt lymphoma | 0/4 | 0 |
| Marginal zone lymphoma | 7/21 | 33 |
| Mantle cell lymphoma | 3/18 | 17 |
| Small lymphocytic lymphoma/CLL | 2/32 | 6 |
| Precursor B-lymphoblastic lymphoma | 1/7 | 14 |
| Plasma cell neoplasms | 0/2 | 0 |
| T-cell lymphoma (N = 35) | ||
| Precursor T-lymphoblastic lymphoma | 0/11 | 0 |
| Peripheral T-cell lymphoma | 10/16 | 62 |
| Anaplastic large cell lymphoma | 1/5 | 20 |
| NK lymphoma | 0/3 | 0 |
| Histiocytic neoplasms (N = 7) | ||
| Langerhan cell histiocytosis | 3/4 | 75 |
| Rosai-Dorfman disease | 3/3 | 100 |
*
Cases were scored positive if more than 30% of lymphoma cells stained for PTP1B.