. Author manuscript; available in PMC: 2009 Oct 1.

Published in final edited form as: Psychoneuroendocrinology. 2008 Aug 15;33(9):1279–1292. doi: 10.1016/j.psyneuen.2008.06.012

Table 3.

Effects of brain DHA content and reproductive status on the affinity and density of serotonin receptors in frontal cortex and hippocampus.

Reproductive status/brain DHA content	B_max (fmol/mg protein)	K_D (nM)
Frontal Cortex
5-HT_1A receptor
Virgin – Normal DHA	93 ± 6.2	1.4 ± 0.23
Virgin – Decreased DHA	98 ± 6.3	1.1 ± 0.16
Parous – Normal DHA	97 ± 8.5	1.2 ± 0.13
Parous – Decreased DHA	95 ± 6.7	1.2 ± 0.17
5-HT_2A receptor
Virgin – Normal DHA	385 ± 48	2.3 ± 0.22
Virgin – Decreased DHA	403 ± 31	1.9 ± 0.23
Parous – Normal DHA	413 ± 23	2.3 ± 0.24
Parous – Decreased DHA	393 ± 21	2.0 ± 0.24
Hippocampus
5-HT_1A receptor
Virgin – Normal DHA	153 ± 8.6	1.2 ± 0.10
Virgin – Decreased DHA	139 ± 15	1.3 ± 0.21
Parous – Normal DHA	129 ± 6.9	0.9 ± 0.11
Parous – Decreased DHA	187 ± 5.4^†^‡	1.5 ± 0.18
5-HT_2A receptor
Virgin – Normal DHA	50 ± 3.8	1.0 ± 0.14
Virgin – Decreased DHA	61 ± 3.3	1.4 ± 0.11
Parous – Normal DHA	57 ± 3.7	1.3 ± 0.09
Parous – Decreased DHA	51 ± 4.2	1.2 ± 0.05

Data are presented as the mean ± SEM (n = 8–10 per group).

^†

Different from Virgin - Decreased DHA (P<0.01).

^‡

Different from Parous - Normal DHA (P<0.01).