Figure 4.
Quantification of apical junction region (AJR) width shows there is exponential growth of AJRs in supporting cells of the sensory epithelium and cells of the nonsensory epithelium as mice develop and mature from embryonic day 18 (E18) to postnatal day 83 (P83). Measurements of the width of AJRs from ≥ 400 junctions in fifteen different age groups of mice for the sensory epithelium and six different age groups for the nonsensory epithelium were taken. AJR width increases 400% in the sensory epithelium (black squares) and 178% in the nonsensory epithelium (open squares). Von Bertalanffy growth curves (red lines) fit the data with high r-squared values, and the data points fall within the 95% confidence intervals (C.I.; blue lines). The parameters for the curve fits all had squared error values less than 0.2. W: AJR width; W∞: AJR width at infinity; C: scaling factor to prevent initial width from equaling zero; k: curvature parameter; t: time in days.