Figure 5.

Kaplan-Meier survival curve for time to incident Alzheimer's disease by adiposity risk status (increase in body mass index (change >90th percentile) during any 5-year interval between ages 30 and 50 years vs. no increase) among men, Baltimore Longitudinal Study of Aging, 1958–2006. The hazard ratio was 3.70 (95% confidence interval: 1.43, 9.56; P < 0.01; log-rank test P = 0.0166). Failure was defined as first diagnosis of incident Alzheimer's disease at or after age 50 years. Hazard ratios were adjusted for education, race/ethnicity, smoking status, and year of birth.