Table 1.
Characteristics of subjects, stimulation, and outcome variables
| Variable | Poor responders (n = 472) | Normal responders (n = 472) |
|---|---|---|
| Mean(±SD) age | 36.6 ± 4.2 | 33.3 ± 4.04* |
| Mean (±SD)duration of infertility | 7.23 ± 4.9 | 7.02 ± 4.8 |
| No.(%) of patients with primary infertility | 287(60.8%) | 282(59.7%) |
| No.(%) of patients with indicated infertility diagnosis | ||
| Tubal factor | 254(53.8%) | 261(55.3%) |
| Male factor | 99(21%) | 112(23.7%) |
| Unexplained | 49(10.4%) | 59(12.5%) |
| Endometriosis | 70(14.8%) | 40(8.5%) |
| Previous ovarian surgery(%) | 64(13.6%) | 13(2.8%)* |
| Mean (±SD) day 2 FSH level (IU/l) | 11.8 ± 5.14 | 8.33 ± 2.89* |
| Mean (±SD) day 2 LH level (IU/l) | 4.41 ± 2.78 | 4.67 ± 2.75 |
| Mean (±SD)day 2 FSH/LH | 3.32 ± 2.56 | 2.19 ± 1.44* |
| Mean (±SD) day 2 E2 level (pmol/l) | 112.4 ± 87.7 | 108.6 ± 43.7 |
| Mean (±SD) day 2 antral follicle count (n) | 4.09 ± 2.49 | 10.1 ± 7.2* |
| Mean (±SD) no. of total ampules | 58.5 ± 15.8 | 40.6 ± 17.0* |
| Mean (±SD) duration of stimulation (day) | 10.8 ± 2.0 | 10.2 ± 1.7 |
| Mean (±SD) peak E2 level (pmol/l) | 3615 ± 2021 | 9042 ± 5674* |
| Mean (±SD) no. of oocytes | 3.45 ± 1.74 | 14.2 ± 6.5* |
| Mean (±SD) fertilization rate (% of oocytes) | 71.0%(1,326/1,867) | 86%(4,919/5,720)* |
| Clinical pregnancy rate (%) | 70(14.8%) | 173(36.7%)* |
*p < 0.05