Table 5.
The allele frequencies of four polymorphisms of CYP1B1 gene between Chinese uterine leiomyoma patients and controls
| SNP | Allele | Cases n = 200 (%) | Control n = 220 (%) | Adjusted OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Arg48Gly | C | 169 (84.5) | 181 (82.3) | 1.00 (Ref.) | – |
| G | 31 (15.5) | 39 (17.7) | 0.85 (0.51–1.43) | 0.541 | |
| Ala119Ser | G | 154 (77.0) | 171 (77.7) | 1.00 (Ref.) | – |
| T | 46 (23.0) | 49 (22.3) | 1.04 (0.66–1.65) | 0.859 | |
| Leu432Val | C | 171 (85.5) | 180 (81.8) | 1.00 (Ref.) | – |
| G | 29 (14.5) | 40 (18.2) | 0.76 (0.45–1.29) | 0.309 | |
| Asp449Asp | C | 175 (87.5) | 180 (81.8) | 1.00 (Ref.) | – |
| T | 25 (12.5) | 40 (18.2) | 0.64 (0.37–1.11) | 0.108 |
OR Odds ratio, 95% CI 95% confidence interval, Ref. reference category