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. Author manuscript; available in PMC: 2008 Nov 11.
Published in final edited form as: J Infect Dis. 2005 Feb 28;191(7):1196–1203. doi: 10.1086/428289

Table 5. Sample 8 genes with transcript levels at least 2-fold greater than those in in vitro 3D7 samples.

Gene Description Expression units
In vivo In vitro 3D7
6 7 8 12 29 M ER LR
Surface proteins
 PFE0005w PfEMP1 114 209 234 184 90 34 95 61
 PF08_0141 PfEMP1 0 90 180 0 0 0 32 0
 MAL6P1.316 PfEMP1 0 106 141 0 0 0 32 21
 PF10_0399 RIFIN 197 356 303 185 58 52 0 32
 PF14_0768 RIFIN 162 290 295 182 144 36 39 28
 PFL0015c RIFIN 104 443 196 162 71 41 0 28
 PFL2660w RIFIN 0 451 177 0 120 40 42 0
 PF11_0515 RIFIN 0 396 174 116 0 0 0 28
 PFI0030c RIFIN 124 185 156 120 53 33 16 21
 PFD0055w RIFIN 46 138 137 108 38 17 0 13
 PF14_0004 RIFIN 77 164 127 77 48 18 0 17
 PFB1010w RIFIN 45 121 115 65 0 19 0 0
 PF13_0007 RIFIN 58 123 106 64 43 0 14 21
 PFA0050c RIFIN 0 0 86 96 0 0 0 0
 PFE0025c RIFIN 0 0 83 73 0 0 0 0
 PFD0130c RIF pseudogene 0 176 77 76 0 30 0 0
 PF10_0394 RIFIN 0 201 45 0 0 0 0 0
 PFA0090c STEVOR 197 263 364 245 0 52 36 0
 PF14_0007 STEVOR, putative 0 200 216 108 81 42 0 30
 PFD0035c STEVOR 57 502 197 189 0 50 0 0
 PFB0955w STEVOR, degenerate, putative 0 450 174 217 0 25 19 0
 PFB0025c STEVOR, putative 0 276 147 0 0 64 0 56
 PF11_0512 RESA-2 530 156 379 443 626 0 0 0
Metabolic/cellular function
 PF13_0045 40S ribosomal protein S27, putative 925 511 1133 1248 1431 0 342 483
 PF14_0183 RNA helicase, putative 480 131 413 1373 227 92 154 128
 PFC0855w Ubiquitin-conjugating enzyme, putative 277 709 396 473 194 0 121 153
 PFC0050c Long-chain fatty acid ligase, putative 617 186 192 73 92 0 0 0
 PFE1265w G-protein coupled receptor, putative 40 405 135 91 0 0 0 0
 PFI1110w Glutamate-ammonia ligase (glutamine synthetase) 79 289 126 109 66 0 52 37
 PF14_0751 Fatty acyl coenzyme A synthetase-1, putative 0 143 80 0 0 0 0 0
 PFI0255c Mitochondrial carrier protein, putative 0 161 62 112 0 0 0 0
 PFI0415c Ribosomal RNA methyltransferase, putative 23 0 42 22 0 0 0 0
 MAL8P1.22 Dehydrodolichyl diphosphate synthetase, putative 26 130 20 0 14 0 0 0
 MAL7P1.92 Cysteine repeat modular protein 2 homologue 0 0 13 0 0 0 0 0
 MAL7P1.164 Adaptor-related protein, putative 0 0 10 18 0 0 0 0
Hypothetical protein
 PF11_0032 Hypothetical protein 1646 3627 3499 2583 1071 774 393 697
 PFA0620c Hypothetical protein 569 211 2950 122 1383 0 913 444
 MAL7P1.39 Hypothetical protein 114 2246 604 504 226 175 105 94
 PFA0135w Hypothetical protein 469 313 577 883 307 229 0 37
 PF11_0033 Hypothetical protein 284 1926 550 544 241 212 49 68
 chr1.rRNA-1-ITS2 Hypothetical protein 147 1021 395 333 96 49 0 0
 PF14_0752 Hypothetical protein 837 0 314 569 351 44 76 23
 PFA0075w Hypothetical protein 0 664 259 195 0 67 0 0
 PFD0065w Hypothetical protein 94 276 233 165 285 31 0 0
 PF10_0383 Hypothetical protein, conserved 111 1063 229 345 120 105 17 33
 MAL8P1.30 Hypothetical protein 118 639 227 206 109 52 28 42
 PF14_0743 Hypothetical protein 119 730 224 174 84 96 0 78
 PFL0720w Hypothetical protein 76 672 201 175 86 69 0 38
 PFA0245w Hypothetical protein 52 626 170 197 68 39 0 0
 PF14_0298 Hypothetical protein 96 215 163 122 0 0 22 0
 PFL1225c Hypothetical protein 0 0 158 0 0 61 0 58
 PF11_0271 Hypothetical protein, conserved 0 360 146 139 58 0 0 71
 PF11_0006 Hypothetical protein 173 1188 142 295 178 0 0 0
 PF14_0562 Hypothetical protein 0 509 135 104 0 0 0 24
 PF14_0539 Hypothetical protein 43 385 133 129 49 37 26 0
 PFC0505c Hypothetical protein 76 536 130 169 74 43 30 48
 PFL0955c Hypothetical protein 0 200 128 102 0 0 0 0
 PFE0030c Hypothetical protein 0 238 114 100 0 18 0 0
 PF13_0230 Hypothetical protein 61 141 100 0 0 0 0 0
 PFB0950w Hypothetical protein 0 289 100 99 0 0 0 0
 PFI0485c Hypothetical protein 55 289 98 144 0 0 0 0
 PF11_0004 Hypothetical protein 49 253 97 152 67 35 16 0
 PF11_0089 Hypothetical protein 0 116 95 0 46 12 0 0
 PFL1660c Hypothetical protein 0 253 90 48 0 23 0 20
 PFA0720w Hypothetical protein 31 365 86 116 0 0 0 0
 PFE0095c Hypothetical protein 0 0 70 0 0 0 0 0
 MAL7P1.52 Hypothetical protein 0 258 63 92 0 0 0 0
 MAL6P1.233 Hypothetical protein 0 0 54 0 0 0 0 0
 PF11_0411 Hypothetical protein 11 163 45 0 0 0 0 0
 PF14_0158 Hypothetical protein 0 205 44 0 0 0 0 0
 PF13_0151 Hypothetical protein 0 0 43 0 0 0 0 0
 mitopl_rpoC Hypothetical protein 0 0 38 0 0 0 0 0
 PFB0395w Hypothetical protein 0 0 37 0 0 0 0 0
 PF07_0109 Hypothetical protein 0 0 34 0 0 0 0 0
 PFB0690w Hypothetical protein 0 0 34 0 0 10 0 0
 MAL7P1.89 Hypothetical protein 0 0 30 22 0 0 0 0
 MAL13P1.179 Hypothetical protein 0 53 28 0 0 0 0 0
 PF14_0558 Hypothetical protein 19 0 27 0 0 0 0 0
 PFL2525c Hypothetical protein 38 182 25 88 0 0 0 0
 PF08_0013 Hypothetical protein 14 0 22 0 0 0 0 0
 PFB0110w Hypothetical protein 0 0 20 0 0 0 0 0
 PF11_0421 Hypothetical protein 0 0 19 15 0 0 0 0
 PFI1785w Hypothetical protein 0 0 18 0 0 0 0 0
 PF13_0012 Hypothetical protein 0 0 18 0 0 0 0 0
 PF14_0521 Hypothetical protein 11 0 18 0 0 0 0 0
 PF13_0038 Hypothetical protein 0 95 18 0 0 0 0 0
 PF14_0202 Hypothetical protein 0 0 17 0 0 0 0 0
 PFE0190c Hypothetical protein 0 0 16 0 0 0 0 0
 PF10_0206 Hypothetical protein 0 0 16 0 0 0 0 0
 PFC0075c Hypothetical protein 18 0 16 32 0 0 0 0
 MAL13P1.32 Hypothetical protein 0 0 16 0 0 0 0 0
 PFL2385c Hypothetical protein 0 0 15 20 0 0 0 0
 PF08_0070 Hypothetical protein 0 0 15 14 0 0 0 0
 PFB0960c Hypothetical protein 0 0 15 0 0 0 0 0
 PF11_0410 Hypothetical protein 0 0 13 11 0 0 0 0
 PF14_0049 Hypothetical protein 0 0 13 0 0 0 0 0
 PF11_0064 Hypothetical protein 0 0 13 0 0 0 0 0
 PF14_0116 Hypothetical protein 16 19 13 12 15 0 0 0
 PFI0815c Hypothetical protein, conserved 0 0 13 0 0 0 0 0
 PF10_0055 Hypothetical protein 0 0 12 0 0 0 0 0
 PFC0215c Hypothetical protein 0 0 12 0 0 0 0 0
 PFA0385w Hypothetical protein 0 121 12 0 0 0 0 0
 PFB0946c Hypothetical protein 0 0 12 0 0 0 0 0
 MAL6P1.187 Hypothetical protein 0 0 12 0 0 0 0 0
 PFE0610c Hypothetical protein 0 0 12 13 0 0 0 0
 PF10_0158 Hypothetical protein 0 0 12 0 0 0 0 0
 PFE0085c Hypothetical protein 0 0 11 0 0 0 0 0
 MAL8P1.41 Hypothetical protein 15 0 11 0 0 0 0 0
 MAL6P1.166 Hypothetical protein 0 11 11 0 0 0 0 0
 PF13_0075 Hypothetical protein 0 17 11 0 0 0 0 0
 PFB0510w Hypothetical protein 0 0 11 23 0 0 0 0
 PF14_0534 Hypothetical protein 0 0 11 0 0 0 0 0
 PFE1180c Hypothetical protein 0 0 11 10 0 0 0 0
 PFL0985c Hypothetical protein 0 24 11 0 12 0 0 0
 PFL2020c Hypothetical protein 0 0 11 0 19 0 0 0
 PFI1305w Hypothetical protein 0 0 11 0 0 0 0 0
 PF11_0462 Hypothetical protein 0 0 11 0 0 0 0 0
 PFB0470w Hypothetical protein 18 0 10 0 0 0 0 0
 PFD0870w Hypothetical protein 0 0 10 0 0 0 0 0
 PFC0130c Hypothetical protein 0 0 10 0 0 0 0 0

NOTE. ER, early ring; LR, late ring; M, merozoite; PfEMP1, erythrocyte membrane protein 1