Table 3.
Experiment 2c – Distance traveled (mean ± SEM) in centimeters on Drug Sessions.
| Drug Session | |||||
|---|---|---|---|---|---|
| Pretrmt with Bupropion | Pretrmt with Nicotine | 1 | 2 | 3 | 4 |
| Vehicle | Vehicle | 2195 (± 141) | 1813 (± 214) | 2129 (± 220) | 1887 (± 262) |
| Nicotine | 1530 (± 234) | 1305 (± 246) | 2057 (± 269) | 1825 (± 210) | |
| 1 Bup | Vehicle | 2194 (± 212) | 1990 (± 307) | 1915 (± 195) | 2106 (± 306) |
| Nicotine | 2231 (± 253) | 2051 (± 157) | 2095 (± 203) | 2530 (± 252) | |
| 5 Bup | Vehicle | 2126 (± 231) | 2403 (± 282) | 2443 (± 254) | 2491 (± 233) |
| Nicotine | 2610 (± 238) | 2487 (± 279) + | 2863 (± 324) | 3181 (± 310) + | |
| 10 Bup | Vehicle | 2256 (± 189) | 2090 (± 202) | 2187 (± 189) | 2157 (± 186) |
| Nicotine | 3325 (± 295) + | 2885 (± 239) + | 3402 (± 230) + | 3447 (± 297) *+ | |
| 20 Bup | Vehicle | 2841 (± 251) | 2568 (± 291) | 3266 (± 358) | 3073 (± 374) |
| Nicotine | 3525 (± 446) *+ | 3197 (± 277) *+ | 4269 (± 488) *+ | 4104 (± 428) *+ | |
The “*” and “+” symbols denote a significant difference from Veh+Veh and Veh+Nic control mice, respectively, on a specific session, p < 0.05.