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Radioligand binding curves for 17. Increasing concentrations of 17 were incubated with the appropriate radioligand (A1: [3H]CCPA, A2A: [3H]CGS21680, A3: [125I]I-AB-MECA) and a suspension of CHO cell membranes (A1 or A3) or HEK cells (A2A) expressing the appropriate receptor. For a summary of Ki values obtained, see Table 1.
